Results 51 to 60 of about 275,247 (311)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Incremental Localization Algorithm Based on Multivariate Analysis

International Journal of Distributed Sensor Networks, 2013
In view of the traditional increment localization method, only the heteroscedasticity caused by the error accumulation is considered unilaterally a kind of incremental localization algorithm based on multivariate analysis is proposed.
Xiaoyong Yan, Huanyan Qian, Jiguang Chen
doaj   +1 more source

Input-Output Benefit Analysis of Green Building Incremental Cost Based on DEA-Entropy Weight Method

Buildings, 2022
Green buildings are an important carrier for the transformation of the construction industry to green, efficient and energy-saving, and an important part of the national sustainable development strategy.
Wei Liu, Xiaohui Huang, Zhuan He, Yongxiang Wang, Luyao Han, Wenxuan Qiu   +5 more
doaj   +1 more source

Incremental Accelerated Kernel Discriminant Analysis [PDF]

Proceedings of the 25th ACM international conference on Multimedia, 2017
In this paper a novel incremental dimensionality reduction (DR) technique called incremental accelerated kernel discriminant analysis (IAKDA) is proposed. Consisting of the eigenvalue decomposition of a relatively small-size matrix and the recursive block Cholesky factorization of the kernel matrix, a nonlinear DR transformation is efficiently computed
Gkalelis, Nikolaos, Mezaris, Vasileios
openaire   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Selective Growth of Homo-Epitaxial Ag-Nano-Layer on Tribo-Assisted-Reorientation

Tribology Online, 2008
The growth process and orientational degree of incremental-Ag films with a thickness of 5, 50 and 500 nm, respectively, on reoriented Ag (111) surface were studied by in-situ reflection high-energy electron diffraction (RHEED).
Minoru Goto, Hiroaki Kobayashi, Koichi Akimoto   +2 more
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

A Tutorial on Incremental Stability Analysis using Contraction Theory [PDF]

Modeling, Identification and Control, 2010
This paper introduces a methodology for differential nonlinear stability analysis using contraction theory (Lohmiller and Slotine, 1998). The methodology includes four distinct steps: the descriptions of two systems to be compared (the plant and the ...
J. Jouffroy, T.I. Fossen
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source