Results 31 to 40 of about 12,689 (257)

Intensive care unit mortality and cost-effectiveness associated with intensivist staffing: a Japanese nationwide observational study

Journal of Intensive Care, 2023
Background Japan has four types of intensive care units (ICUs) that are divided into two categories according to the management fee charged per day: ICU management fees 1 and 2 (ICU1/2) (equivalent to high-intensity staffing) and 3 and 4 (ICU3/4 ...
Saori Ikumi, Takuya Shiga, Takuya Ueda, Eichi Takaya, Yudai Iwasaki, Yu Kaiho, Kunio Tarasawa, Kiyohide Fushimi, Yukiko Ito, Kenji Fujimori, Masanori Yamauchi   +10 more
doaj   +1 more source

The Cost-Effectiveness of Avatrombopag Versus Eltrombopag and Romiplostim in the Treatment of Patients with Immune Thrombocytopenia in the UK

Journal of Market Access & Health Policy
Background: Thrombopoietin receptor agonists—romiplostim, eltrombopag and avatrombopag—are commonly used as second-line treatments for immune thrombocytopenia (ITP).
Nichola Cooper, Sebastian Guterres, Michał Pochopień, Koo Wilson, Sam James, Mondher Toumi, Anna Tytuła, Carly Rich, Daniel Eriksson   +8 more
doaj   +1 more source

How to assess the value of medicines?

Frontiers in Pharmacology, 2010
This study aims to discuss approaches to assessing the value of medicines. Economic evaluation assesses value by means of the incremental cost-effectiveness ratio (ICER).
Steven Simoens
doaj   +1 more source

Cost-effectiveness of the Perioperative Pain Management Bundle a registry-based study

Frontiers in Public Health, 2023
IntroductionThe Perioperative Pain Management Bundle was introduced in 10 Serbian PAIN OUT network hospitals to improve the quality of postoperative pain management. The Bundle consists of 4 elements: informing patients about postoperative pain treatment
Suzana Bojic, Suzana Bojic, Nebojsa Ladjevic, Nebojsa Ladjevic, Ivan Palibrk, Ivan Palibrk, Ivan Soldatovic, Ivana Likic-Ladjevic, Ivana Likic-Ladjevic, Winfried Meissner, Ruth Zaslansky, Ulrike M Stamer, Philipp Baumbach, Dusica Stamenkovic, Dusica Stamenkovic   +14 more
doaj   +1 more source

Comparing the cost effectiveness of harm reduction strategies : a case study of the Ukraine [PDF]

, 2014
Background Harm reduction strategies commonly include needle and syringe programmes (NSP), opioid substitution therapy (OST) and interventions combining these two strategies. Despite the proven effectiveness of harm-reduction strategies in reducing human
Kim, Sung, Sung Kim, Pulkki-Brannstrom, AM, Jolene Skordis-Worrall, Pulkki-Brännström, Anni-Maria,, Kim, SW, Anni-Maria Pulkki-Brannstrom, Pulkki-Brännström, Anni-Maria, Skordis-Worrall, J, Skordis-Worrall, Jolene   +9 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Cost-Effectiveness of Cetuximab for Advanced Esophageal Squamous Cell Carcinoma. [PDF]

PLoS ONE, 2016
BACKGROUND:Costly biologicals in palliative oncology are emerging at a rapid pace. For example, in patients with advanced esophageal squamous cell carcinoma addition of cetuximab to a palliative chemotherapy regimen appears to improve survival.
Vincent T Janmaat, Marco J Bruno, Suzanne Polinder, Sylvie Lorenzen, Florian Lordick, Maikel P Peppelenbosch, Manon C W Spaander   +6 more
doaj   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Cost‐Effectiveness of Arthroscopic Partial Meniscectomy and Physical Therapy for Degenerative Meniscal Tear

ACR Open Rheumatology, 2022
Objective We examined the cost‐effectiveness of treatment strategies for concomitant meniscal tear and knee osteoarthritis (OA) involving arthroscopic partial meniscectomy surgery and physical therapy (PT). Methods We used the Osteoarthritis Policy Model,
Emma E. Williams, Jeffrey N. Katz, Valia P. Leifer, Jamie E. Collins, Tuhina Neogi, Lisa G. Suter, Bruce Levy, Alexander Farid, Clare E. Safran‐Norton, A. David Paltiel, Elena Losina   +10 more
doaj   +1 more source

MitraClip for the treatment of heart failure with mitral regurgitation: A cost-effectiveness analysis in a Chinese setting

Frontiers in Cardiovascular Medicine, 2022
BackgroundHeart failure (HF) with mitral regurgitation is associated with decreased survival. Guideline-directed medical therapy and transcatheter edge-to-edge repair (TEER) are the main options for HF patients with severe mitral regurgitation who are ...
Wengang Xia, Kangning Han, Yake Lou
doaj   +1 more source