Results 91 to 100 of about 199,658 (311)

A cost-utility analysis of newborn screening for spinal muscular atrophy in Canada

Orphanet Journal of Rare Diseases
Background Spinal muscular atrophy (SMA) is a neuromuscular disorder caused by the loss of the SMN1 gene, with an estimated birth prevalence of about 1 in 10,000. Early intervention with disease-modifying therapies (DMTs) significantly improves outcomes.
Alex Pace, Weston Roda, Corrina Poon, Hugh J. McMillan, Maryam Oskoui, Alex MacKenzie, Pranesh Chakraborty, Jeff Round   +7 more
doaj   +1 more source

Displacement and Vibration Measurements with Interferometers: Benchmark Configurations, Performance, and R&D Opportunities

Advanced Photonics Research, EarlyView.
Self‐mixing interferometry is a powerful technique that brings together the exceptional sensitivity of phase measurements with the unequalled simplicity of the self‐mix configuration based on modulation of the cavity field induced by the return from the target. According to the selected measurand, displacement or vibration, and to the analog of digital
Silvano Donati
wiley   +1 more source

Cost-effectiveness Analysis of Dupilumab for the Treatment of Adult Patients with Severe Prurigo Nodularis in Italy

Acta Dermato-Venereologica
Prurigo nodularis is characterized by intensely pruritic nodules that significantly impact patients’ quality of life. This study aims to evaluate the cost-effectiveness of dupilumab compared with the best supportive care for the treatment of severe ...
Cataldo Patruno, Massimiliano Povero, Andrea Tassone, Maria Paola Pedone, Donia Bahloul, Jules Tavi, Paolo Amerio   +6 more
doaj   +1 more source

Cost-effectiveness of varicella vaccination program in Iran

International Journal of Preventive Medicine, 2017
Background: Varicella zoster virus is the etiologic agent of primary varicella (chickenpox) during childhood, and varicella vaccination has not been introduced in Iran.
Shooka Esmaeeli, Mohsen Yaghoubi, Marzieh Nojomi   +2 more
doaj   +1 more source

Elimination of Necking and Aspect Ratio Dependence in Uniaxial Actuators by Continuous Fiber Reinforcement

Advanced Robotics Research, EarlyView.
A novel carbon fiber reinforcement for dielectric elastomer actuators enhances actuation force while decoupling electromechanical performance from the actuator's aspect ratio. Unlike conventional fiber reinforcements, it enables a uniform planar stretch state along the entire actuator.
Markus Koenigsdorff, Stefania Konstantinidi, Anett Endesfelder, Petr Osipov, Johannes Mersch, E.‐F. Markus Vorrath, Martina Zimmermann, Yves Perriard, Gerald Gerlach   +8 more
wiley   +1 more source

Cost-Effectiveness of Humidified High-Flow Therapy (HHFT) for COPD Patients on Long-Term Oxygen Therapy [Corrigendum]

ClinicoEconomics and Outcomes Research, 2023
Groessl EJ, Tally SR, Hillery N. Clinicoecon Outcomes Res. 2023;15:239—250. Page 244, Results, first paragraph, the text “The main results of the Markov decision tree model are presented in Table 2.
Groessl EJ, Tally SR, Hillery N
doaj  

Design Optimization of a Variable Stiffness Robotic Gripper with Passive Restoration Fabricated by Multimaterial 3D Printing

Advanced Robotics Research, EarlyView.
A multimaterial robotic gripper fabricated via multimaterial 3D printing integrates conductive thermopolymer joints with flexible elastomeric components. Joule heating enables precise joint‐level stiffness modulation, enhanced by embedded temperature sensors, passive shape restoration, and active cooling, enabling versatile manipulation capabilities ...
Daniel Jee Seng Goh, Guo Liang Goh, Selvanther Sivarajan, Van Pho Nguyen, Wai Yee Yeong   +4 more
wiley   +1 more source

Reconstruction versus conservative treatment after rupture of the anterior cruciate ligament: cost effectiveness analysis

BMC Health Services Research, 2011
Background The decision whether to treat conservatively or reconstruct surgically a torn anterior cruciate ligament (ACL) is an ongoing subject of debate.
Farshad Mazda, Gerber Christian, Meyer Dominik C, Schwab Alexander, Blank Patricia R, Szucs Thomas   +5 more
doaj   +1 more source

Continuum Mechanics Modeling of Flexible Spring Joints in Surgical Robots

Advanced Robotics Research, EarlyView.
A new mechanical model of a tendon‐actuated helical extension spring joint in surgical robots is built using Cosserat rod theory. The model can implicitly handle the unknown contacts between adjacent coils and numerically predict spring shapes from straight to significantly bent under actuation forces.
Botian Sun, Liang Zhang, Jianwen Zeng, Xuefeng Wang   +3 more
wiley   +1 more source

Automated Screening for Three Inborn Metabolic Disorders: A Pilot Study

Online Journal of Health & Allied Sciences, 2006
Background: Inborn metabolic disorders (IMDs) form a large group of rare, but often serious, metabolic disorders. Aims: Our objective was to construct a decision tree, based on classification algorithm for the data on three metabolic disorders, enabling ...
Kavitha S, Sarbadhikari SN, Ananth N Rao
doaj