Results 121 to 130 of about 300,914 (309)

Identification and Drug Screening of Single Cells from Human Tumors on Semiconductor Chip for Cancer Precision Medicine

Advanced Science, EarlyView.
The study innovatively integrates single‐cell electric impedance identification and drug screening on a semiconductor chip, addressing tumor heterogeneity limitations. The system achieves label‐free cancer cell recognition while concurrently evaluating drug efficacy on cancer cells and toxicity on noncancerous cells.
Wenhao Hui, Ka‐Meng Lei, Yingying Liu, Xinru Huang, Yunlong Zhong, Xiaojun Chen, Mingji Wei, Jie Yan, Ren Shen, Pui‐In Mak, Rui P. Martins, Shuhong Yi, Ping Wang, Yanwei Jia   +13 more
wiley   +1 more source

Cost-effectiveness analysis of extended thromboprophylaxis with rivaroxaban versus no prophylaxis in high-risk patients after hospitalisation for COVID-19: an economic modelling studyResearch in context

The Lancet Regional Health. Americas, 2023
Summary: Background: In patients at high risk of thromboembolism who were discharged after hospitalisation due to COVID-19, thromboprophylaxis with rivaroxaban 10 mg/day for 35 days significantly improved clinical outcomes, reducing thrombotic events ...
Caroline Cândida Carvalho de Oliveira, Leandro Barile Agati, Camilla Moreira Ribeiro, Valéria Cristina Resende Aguiar, Roberto Augusto Caffaro, Marisa da Silva Santos, Ricardo Ribeiro Alves Fernandes, Carlos Alberto da Silva Magliano, Alfonso Tafur, Alex C. Spyropoulos, Renato Delascio Lopes, Jawed Fareed, Eduardo Ramacciotti   +12 more
doaj  

deepTFBS: Improving within‐ and Cross‐Species Prediction of Transcription Factor Binding Using Deep Multi‐Task and Transfer Learning

Advanced Science, EarlyView.
DeepTFBS leverages deep learning to predict transcription factor binding sites across species, integrating multi‐task and transfer learning approaches to improve performance in data‐scarce scenarios. This study demonstrates enhanced accuracy in intra‐ and cross‐species prediction, revealing conserved regulatory patterns and functional variants.
Jingjing Zhai, Yuzhou Zhang, Chujun Zhang, Xiaotong Yin, Minggui Song, Chenglong Tang, Pengjun Ding, Zenglin Li, Chuang Ma   +8 more
wiley   +1 more source

Cost-effectiveness of edaravone dexborneol versus human urinary kallidinogenase for acute ischemic stroke in China

Health Economics Review
Background Clinical trials have demonstrated the efficacy of edaravone dexborneol in the treatment of acute ischemic stroke. This study aims to determine the cost-effectiveness of edaravone dexborneol compared with human urinary kallidinogenase from ...
Pingyu Chen, Mengjie Luo, Yanqiu Chen, Yanlei Zhang, Chao Wang, Hongchao Li   +5 more
doaj   +1 more source

Solving Problems of Imperfect Data Streams by Incremental Decision Trees

Journal of Emerging Technologies in Web Intelligence, 2013
Big data is a popular topic that attracts highly attentions of researchers from all over the world. How to mine valuable information from such huge volumes of data remains an open problem. Although fast development of hardware is capable of handling much larger volume of data than ever before, in the author’s opinion, a well-designed algorithm is ...
openaire   +2 more sources

Twin Toughening‐Driven Martensitic Transformation Strategy Synergistic Improvement for Plasticity‐Thermal Shock Resistance of (Hf─Zr─Ti)C Ceramic Coating in Severe Thermal Environments

Advanced Science, EarlyView.
A “ceramic self‐toughening strategy” is introduced for enhancing the plasticity and thermal shock resistance of (Hf─Zr─Ti)C coatings through twin toughening‐driven martensitic transformations in oxide scales. It facilitated the formation of stable, dense, and high‐toughness oxide scales after repeat ablation, and endowed prepared coatings with superior
Jiachen Li, Yulei Zhang, Yanqin Fu, Tao Li, Jian Zhang, Deyu Yang, Lingfei Cao, Fanyu Lu, Junhao Zhao, Junshuai Lv, Hejun Li   +10 more
wiley   +1 more source

Structural Variations Associated with Adaptation and Coat Color in Qinghai‐Tibetan Plateau Cattle

Advanced Science, EarlyView.
This study reveals the landscape of structural variants in Qinghai‐Tibetan Plateau cattle through long‐read sequencing. Discoveries include metabolic and oxygen‐regulation gene variants, along with a 2‐Mb KIT‐containing inversion and translocations responsible for cattle gray coat. These findings highlight the significant role of structural variants in
Xiaoting Xia, Fuwen Wang, Xiaoyu Luo, Shuang Li, Yang Lyu, Yining Zheng, Zhijie Ma, Kaixing Qu, Rende Song, Jianyong Liu, Jicai Zhang, Basang Wangdui, Basang Zhuzha, Suolang Quji, Li Zhao, Silang Wangmu, Ciren Luobu, Nima Cangjue, Danzeng Luosang, Suolang Sizhu, Haijian Cheng, Ruizhe Li, Zhipeng Wu, Ruihua Dang, Yongzhen Huang, Xianyong Lan, Luohao Xu, Haifei Hu, WaiYee Low, Zhuqing Zheng, Yu Wang, Yuanpeng Gao, Lu Deng, Johannes A. Lenstra, Jianlin Han, Xueyi Yang, Wenfa Lyu, Bizhi Huang, Chuzhao Lei, Ningbo Chen   +39 more
wiley   +1 more source

Targeted Intervention Strategies for Maternal–Offspring Transmission of Christensenellaceae in Pigs via a Deep Learning Model

Advanced Science, EarlyView.
This study deciphers maternal‐driven microbial transmission in pigs using a deep learning model (maternal–offspring microbial transmission model), identifying Christensenellaceae R‐7 group as a key transmitted taxon. Filtered galacto‐oligosaccharides‐targeted Christensenellaceae R‐7 group alters offspring microbial functions via maternal ...
Haibo Shen, Xiaokang Ma, Longlin Zhang, Hao Li, Jichang Zheng, Shengru Wu, Ke Zuo, Yulong Yin, Jing Wang, Bie Tan   +9 more
wiley   +1 more source

Thermo‐Responsive Tri‐State Photonic Crystals

Advanced Science, EarlyView.
Tri‐state photonic crystals combine thermochromic structural color, fluorescence, and afterglow via far‐field absorption tuning, bypassing the efficiency‐lifetime trade‐off of TS‐FRET. This enables dynamic, high‐capacity anti‐counterfeiting with tunable optical states.
Yuewei Zheng, Jinqing Chen, Wanqi Mo, Wei Hong   +3 more
wiley   +1 more source

Incremental Generation of A Decision Tree Using Global Discretization For Large Data [PDF]

, 2005
Kyong-Sik Han, Soo-Won Lee
openalex   +1 more source