Results 71 to 80 of about 12,148 (269)

Anisotropic Surface Microrollers for Endovascular Navigation: A Computational Analysis with a Case Study in Hepatic Perfusion

Advanced Theory and Simulations, EarlyView.
Computational fluid dynamics analyses assess the upstream locomotion performance of anisotropic microrollers with varying height‐to‐width ratios. Observing their successful upstream locomotion in veins, their performance in hepatic circulation is investigated for treating primary liver cancer.
Burak Arslan, Ugur Bozuyuk, Kıvanç Görgülü, Erdost Yildiz, Hakancan Ozturk, Lucia Liotta, Volker Heinemann, Hana Algül, Metin Sitti   +8 more
wiley   +1 more source

Assessment and Comparative Study of Free and Commercial Numerical Software Packages for Lithium‐Ion Battery Modeling

Advanced Theory and Simulations, EarlyView.
This study evaluates the simulation capabilities of lithium‐ion battery (LIB) electrochemical simulation software packages. The benchmark simulation results reveal the impacts of parameter sensitivity to solver performance and stability. The guidelines to troubleshooting common solver failures at high current rates lowers the steep learning curve to ...
Kenneth C. Nwanoro, Michael P. Mercer, Harry E. Hoster   +2 more
wiley   +1 more source

Design, Simulation, and Fabrication of High‐Performance Metamaterial Absorber for EMI Mitigation and THz NDT/Imaging Applications: A Shape‐Preserved GHz‐to‐THz Transition Approach

Advanced Theory and Simulations, EarlyView.
A novel metamaterial absorber is designed, simulated, and validated for both 5G mmWave and THz applications, achieving >95.8% and 90% absorption, respectively. Its polarization‐insensitive, scalable design enables applications in THz NDT, imaging, and EMI shielding.
Ahmet Teber
wiley   +1 more source

Cost-effectiveness analysis of XELOX versus XELOX plus bevacizumab for metastatic colorectal cancer in a public hospital school

BMC Cancer, 2017
Background Metastatic colorectal cancer imposes a substantial burden on patients and society. Over the last years, progresses in the treatment have been made especially due to the introduction of monoclonal antibodies, such as bevacizumab which, on the ...
Andrea Queiróz Ungari, Leonardo Régis Leira Pereira, Altacílio Aparecido Nunes, Fernanda Maris Peria   +3 more
doaj   +1 more source

Non‐Invasive Diagnosis of Chronic Myocardial Infarction via Composite In‐Silico‐Human Data Learning

Advanced Science, EarlyView.
This study presents a non‐invasive machine learning model to identify infarct regions in the left ventricle using cardiac strain data. By combining rodent‐based simulated data with limited human data, the model achieves high accuracy in predicting infarct size and location without the need for gadolinium contrast agents, offering a promising ...
Rana Raza Mehdi, Nikhil Kadivar, Tanmay Mukherjee, Emilio A. Mendiola, Akila Bersali, Dipan J. Shah, George Karniadakis, Reza Avazmohammadi   +7 more
wiley   +1 more source

The DEC2‐SCN2A Axis is Essential for the Anticonvulsant Effects of Cannabidiol by Modulating Neuronal Plasticity

Advanced Science, EarlyView.
This study identifies DEC2 as a critical transcriptional repressor of Scn2a that directly binds E‐box motifs in its promoter to regulate neuronal plasticity and epileptogenesis. Functional manipulation of DEC2 alters seizure susceptibility in vivo. Cannabidiol enhances this repression, unveiling a novel DEC2‐SCN2A axis underlying its anticonvulsant ...
Huifang Song, Yifan Wang, Lili Wang, Chang Guo, Shiqi Liu, Yi Rong, Jiawen Tian, Chao Peng, Yuying Shao, Zhixiong Ma, Na Li, Jingliang Zhang, Zijun Peng, Xu Yan, Hangwei Fa, Xinyue Ma, Jie Dong, Jinping Ji, Chen Yang, Haocheng Chen, Jing Liang, Qi Sun, Yang Yang, Weining Ma, Zhuo Huang   +24 more
wiley   +1 more source

From Code to Life: The AI‐Driven Revolution in Genome Editing

Advanced Science, EarlyView.
This review explores AI‐driven advancements in genome editing, focusing on CRISPR optimization, enhanced targeting precision, reduced off‐target effects, and novel tool design. It addresses ethical challenges, data biases, and highlights future prospects in precision medicine, agriculture, and synthetic biology.
Zhidong Li, Wasi Ullah Khan, Genxiang Bai, Chao Dong, Jungang Wang, Youpeng Zhang, Chong Wang, Hongbin Zhang, Wenyi Wang, Ming Luo, Fei Chen   +10 more
wiley   +1 more source

A cost-utility analysis of newborn screening for spinal muscular atrophy in Canada

Orphanet Journal of Rare Diseases
Background Spinal muscular atrophy (SMA) is a neuromuscular disorder caused by the loss of the SMN1 gene, with an estimated birth prevalence of about 1 in 10,000. Early intervention with disease-modifying therapies (DMTs) significantly improves outcomes.
Alex Pace, Weston Roda, Corrina Poon, Hugh J. McMillan, Maryam Oskoui, Alex MacKenzie, Pranesh Chakraborty, Jeff Round   +7 more
doaj   +1 more source

Cost-Effectiveness of Humidified High-Flow Therapy (HHFT) for COPD Patients on Long-Term Oxygen Therapy [Corrigendum]

ClinicoEconomics and Outcomes Research, 2023
Groessl EJ, Tally SR, Hillery N. Clinicoecon Outcomes Res. 2023;15:239—250. Page 244, Results, first paragraph, the text “The main results of the Markov decision tree model are presented in Table 2.
Groessl EJ, Tally SR, Hillery N
doaj  

Cost-effectiveness of varicella vaccination program in Iran

International Journal of Preventive Medicine, 2017
Background: Varicella zoster virus is the etiologic agent of primary varicella (chickenpox) during childhood, and varicella vaccination has not been introduced in Iran.
Shooka Esmaeeli, Mohsen Yaghoubi, Marzieh Nojomi   +2 more
doaj   +1 more source