Results 61 to 70 of about 28,526 (253)

Cancer staging diagnosis based on transcriptomics and variational autoencoder

open access: yes陆军军医大学学报
Objective‍ ‍To conduct an in-depth analysis and feature extraction of the transcriptomics data of 10 types of cancers in order to realize the staging diagnosis of cancer samples. Methods‍ ‍The transcriptomics data of the top 10 cancers having the highest
LI Jiarui, QIAN Li, SHEN Junjie
doaj   +1 more source

Immunosignature Screening for Multiple Cancer Subtypes Based on Expression Rule

open access: yesFrontiers in Bioengineering and Biotechnology, 2019
Liquid biopsy (i.e., fluid biopsy) involves a series of clinical examination approaches. Monitoring of cancer immunological status by the “immunosignature” of patients presents a novel method for tumor-associated liquid biopsy. The major work content and
Lei Chen   +9 more
doaj   +1 more source

Moderators of the Effects of Exercise and Manual Therapy for People With Knee and Hip Osteoarthritis: A Secondary Analysis of a Randomized Clinical Trial

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to investigate potential moderators influencing the effects of manual therapy and exercise therapy on pain and functional outcomes in individuals with knee and/or hip osteoarthritis, using data from the MOA trial. This is a secondary analysis of data from the MOA trial that compares the clinical effectiveness of manual ...
Daniel Cury Ribeiro   +2 more
wiley   +1 more source

Risk of Retinopathy Associated with Long‐Term Use of Hydroxychloroquine in Patients with Rheumatic Diseases: A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective We aimed to estimate the prevalence and cumulative incidence of hydroxychloroquine retinopathy (HCQ‐R) and its risk factors among patients receiving long‐term HCQ with rheumatic diseases through a systematic review and meta‐analysis of observational studies that used spectral‐domain optical coherence tomography (SD‐OCT) for screening ...
Narsis Daftarian   +4 more
wiley   +1 more source

Identify Key Sequence Features to Improve CRISPR sgRNA Efficacy

open access: yesIEEE Access, 2017
The CRISPR/Cas9 system is a creative and innovative gene editing biotechnology tool in genetic engineering. Although several achievements have been attained using the CRISPR/Cas9 system, it is still a challenge to avoid off-target effects and improve the
Lei Chen   +7 more
doaj   +1 more source

Associations of Rheumatoid Arthritis Disease Activity With Frailty Over Five Years of Follow‐up

open access: yesArthritis Care &Research, EarlyView.
Objective To evaluate whether rheumatoid arthritis (RA) disease activity is associated with frailty both in cross‐section and longitudinally. Methods Participants within the Veterans Affairs Rheumatoid Arthritis (VARA) registry enrolled from 2003 to 2022 were included.
Courtney N. Loecker   +14 more
wiley   +1 more source

TWISS: A Hybrid Multi-Criteria and Wrapper-Based Feature Selection Method for EMG Pattern Recognition in Prosthetic Applications

open access: yesAlgorithms
This paper proposes TWISS (TOPSIS + Wrapper Incremental Subset Selection), a novel hybrid feature selection framework designed for electromyographic (EMG) pattern recognition in upper-limb prosthetic control.
Aura Polo   +4 more
doaj   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

open access: yesArthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos   +2 more
wiley   +1 more source

Clinical, Histologic, and Serological Predictors of Renal Function Loss in Lupus Nephritis

open access: yesArthritis Care &Research, EarlyView.
Objective Kidney survival is the ultimate goal in lupus nephritis (LN) management, but long‐term predictors remain inadequately studied, requiring long‐term follow‐up. This study aimed to identify baseline and early longitudinal predictors of kidney survival in the Accelerating Medicines Partnership LN longitudinal cohort.
Shangzhu Zhang   +21 more
wiley   +1 more source

An Incremental Mutual Information-Selection Technique for Early Ransomware Detection

open access: yesInformation
Ransomware attacks have emerged as a significant threat to critical data and systems, extending beyond traditional computers to mobile and IoT/Cyber–Physical Systems.
Mazen Gazzan, Frederick T. Sheldon
doaj   +1 more source

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