Results 51 to 60 of about 300,807 (294)

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Early CRT monitoring using time-domain optical coherence tomography does not add to visual acuity for predicting visual loss in patients with central retinal vein occlusion treated with intravitreal ranibizumab:A secondary analysis of trial data [PDF]

, 2017
Our primary purpose was to assess the clinical (predictive) validity of central retinal thickness (CRT) and best corrected visual acuity (BCVA) at 1 week and 1 month after starting treatment with ranibizumab for central retinal vein occlusion.
Bell, Katy J L, Duerr, Hans Peter, Farris, Maria, Glasziou, Paul, Hayen, Andrew, Irwig, Les, Mitchell, Andrew S., Mitchell, Paul, Wright, Jonathan   +8 more
core   +2 more sources

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Photographic Assessment of Change in Trichotillomania: Psychometric Properties and Variables Influencing Interpretation [PDF]

, 2016
Although photographic assessment has been found to be reliable in assessing hair loss in Trichotillomania, the validity of this method is unclear, particularly for gauging progress in treatment.
Compton, Scott N., Franklin, Maddison R., Franklin, Martin E., Houghton, David C., Neal-Barnett, Angela M., Saunders, Stephen M., Twohig, Michael P., Woods, Douglas W.   +7 more
core   +1 more source

Integrating curriculum-based dynamic assessment in computerized adaptive testing: Development and predictive validity of the EDPL-BAI battery on reading competence [PDF]

, 2018
In recent decades, there have been significant changes in the conceptualization of reading as well as in the perception of how this activity should be assessed.
Conejo Muñoz, Ricardo, Fuente Arias, Jesús Enrique de la, Guzmán de los Riscos, Eduardo Francisco, Martella, Diana, Mourgues Codern, Catalina, Navarro Hidalgo, Juan José, Rodríguez Ortiz, Isabel de los Reyes, Saracostti, Mahia, Sánchez Gutiérrez, Claudia   +8 more
core   +4 more sources

Preferences for post‐traumatic osteoarthritis prevention strategies in individuals with anterior cruciate ligament injury

Arthritis Care &Research, Accepted Article.
Objectives There is growing interest in evaluating new strategies to delay or prevent post‐traumatic osteoarthritis (PTOA) in individuals who have sustained anterior cruciate ligament (ACL) injury. This study sought to determine characteristics of potential treatments that are acceptable to patients with ACL injury.
Kevin Kennedy, Lily Waddell, Adam Easterbrook, Jeffrey N. Katz, Cale Jacobs, Morgan Jones, Faith Selzer, Elena Losina, Liana Fraenkel, Nick Bansback   +9 more
wiley   +1 more source

The Validity of Ultra-Short-Term Heart Rate Variability during Cycling Exercise

Sensors, 2023
Ultra-short-term heart rate variability (HRV) has been validated in the resting state, but its validity during exercise is unclear. This study aimed to examine the validity in ultra-short-term HRV during exercise considering the different exercise ...
Yukiya Tanoue, Shihoko Nakashima, Tomohiro Komatsu, Miki Kosugi, Saki Kawakami, Shotaro Kawakami, Ryoma Michishita, Yasuki Higaki, Yoshinari Uehara   +8 more
doaj   +1 more source

A Five-Factor Measure of Obsessive-Compulsive Personality Traits. [PDF]

, 2012
The current study provides convergent, discriminant, and incremental validity data for the Five-Factor Obsessive-Compulsive Inventory (FFOCI), a newly-developed measure of traits relevant to obsessive-compulsive personality disorder (OCPD) from the ...
Lynam, Donald R, Miller, Joshua D, Riddell, Ashley D.B., Samuel, Douglas B, Widiger, Thomas A   +4 more
core   +3 more sources

Handling Concept Drift for Predictions in Business Process Mining [PDF]

, 2020
Predictive services nowadays play an important role across all business sectors. However, deployed machine learning models are challenged by changing data streams over time which is described as concept drift.
Baier, Lucas, Kühl, Niklas, Reimold, Josua   +2 more
core   +3 more sources