Results 91 to 100 of about 1,196,290 (284)

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Nidificación del Chinchero Escamado (Lepidocolaptes falcinellus) [PDF]

open access: yes, 2011
We provide the first description of the nest of the Scalloped Woodcreeper (Lepidocolaptes falcinellus), its clutch size, nestlings, and nesting behavior from prospecting to fledging, based on 102 h of observation at a nest in the subtropical Atlantic ...
Bodrati, Alejandro   +1 more
core  

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Probable Longer Incubation Period for Elderly COVID-19 Cases: Analysis of 180 Contact Tracing Data in Hubei Province, China

open access: yesRisk Management and Healthcare Policy, 2020
Jingyi Dai,1 Lin Yang,2 Jun Zhao2 1Department of Infectious Diseases, The Third People’s Hospital of Kunming City, Kunming, Yunnan Province, People’s Republic of China; 2School of Public Health and Management, Hubei University of Medicine ...
Dai J, Yang L, Zhao J
doaj  

Transmission of scrapie prions to primate after an extended silent incubation period [PDF]

open access: yes, 2015
Citation: Comoy, E. E., Mikol, J., Luccantoni-Freire, S., Correia, E., Lescoutra-Etchegaray, N., Durand, V., . . . Deslys, J. P. (2015). Transmission of scrapie prions to primate after an extended silent incubation period. Scientific Reports, 5.
Andreoletti, O.   +14 more
core   +3 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Epidemiological and clinical differences of coronavirus disease 2019 patients with distinct viral exposure history

open access: yesVirulence, 2020
Since severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread from the early epicenter, Wuhan, to the rest of China, the virulence of SARS-CoV-2 might have evolved at different phases of the pandemic. We therefore compared the unique features
Yinjie Gao   +11 more
doaj   +1 more source

Characterization of erosion of metallic materials under cavitation attack in a mineral oil [PDF]

open access: yes
Cavitation erosion and erosion rates of eight metallic materials representing three crystal structures were studied using a 20-kHz ultrasonic magnetostrictive oscillator in viscous mineral oil.
Buckley, D. H., Rao, B. C. S.
core   +1 more source

When the sun never sets: diverse activity rhythms under continuous daylight in free-living arctic-breeding birds [PDF]

open access: yes, 2013
Circadian clocks are centrally involved in the regulation of daily behavioural and physiological processes. These clocks are synchronized to the 24-hour day by external cues (Zeitgeber), the most important of which is the light-dark cycle.
Helm, B.   +5 more
core   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

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