Results 91 to 100 of about 1,196,290 (284)
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Nidificación del Chinchero Escamado (Lepidocolaptes falcinellus) [PDF]
We provide the first description of the nest of the Scalloped Woodcreeper (Lepidocolaptes falcinellus), its clutch size, nestlings, and nesting behavior from prospecting to fledging, based on 102 h of observation at a nest in the subtropical Atlantic ...
Bodrati, Alejandro +1 more
core
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
Jingyi Dai,1 Lin Yang,2 Jun Zhao2 1Department of Infectious Diseases, The Third People’s Hospital of Kunming City, Kunming, Yunnan Province, People’s Republic of China; 2School of Public Health and Management, Hubei University of Medicine ...
Dai J, Yang L, Zhao J
doaj
Transmission of scrapie prions to primate after an extended silent incubation period [PDF]
Citation: Comoy, E. E., Mikol, J., Luccantoni-Freire, S., Correia, E., Lescoutra-Etchegaray, N., Durand, V., . . . Deslys, J. P. (2015). Transmission of scrapie prions to primate after an extended silent incubation period. Scientific Reports, 5.
Andreoletti, O. +14 more
core +3 more sources
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Since severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread from the early epicenter, Wuhan, to the rest of China, the virulence of SARS-CoV-2 might have evolved at different phases of the pandemic. We therefore compared the unique features
Yinjie Gao +11 more
doaj +1 more source
Characterization of erosion of metallic materials under cavitation attack in a mineral oil [PDF]
Cavitation erosion and erosion rates of eight metallic materials representing three crystal structures were studied using a 20-kHz ultrasonic magnetostrictive oscillator in viscous mineral oil.
Buckley, D. H., Rao, B. C. S.
core +1 more source
When the sun never sets: diverse activity rhythms under continuous daylight in free-living arctic-breeding birds [PDF]
Circadian clocks are centrally involved in the regulation of daily behavioural and physiological processes. These clocks are synchronized to the 24-hour day by external cues (Zeitgeber), the most important of which is the light-dark cycle.
Helm, B. +5 more
core +1 more source
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source

