Results 41 to 50 of about 3,060 (247)

Neuron‐Derived MIF Engages VCAM1 to Fuel a Self‐Amplifying CXCL8 Loop That Drives Perineural Invasion and Metastasis in Gastric Cancer

Advanced Science, EarlyView.
Neuron‐derived MIF binds VCAM1 on gastric cancer cells and activates ERK/STAT3 signaling, leading to CXCL8 transcription and secretion. Tumor‐derived CXCL8 subsequently stimulates neuronal CXCR2 to enhance MIF production, establishing a self‐amplifying MIF–VCAM1–CXCL8 positive‐feedback loop that promotes perineural invasion, tumor progression, and ...
Xunjun Li, Zhongya Zhai, Haiyi Yu, Renjie Qiu, Fengyu Li, Luxi Xiao, Boxi Huang, Huiying Liu, Jiayong He, Bowen Cai, Jiawen Chen, Jiang Yu, Guoxin Li, Tao Chen   +13 more
wiley   +1 more source

Recent Advances in Carbon Cathode Materials toward High‐Performing Zinc‐Ion Hybrid Supercapacitors

Advanced Science, EarlyView.
Aqueous zinc‐ion hybrid supercapacitors (ZHSCs) have emerged as promising next‐generation electrochemical energy‐storage devices. Porous carbon materials have been extensively studied as cathodes, with advances in tailoring pore structures and material properties to enhance performance.
Take Hirooka, Zhaolin Liu, Ivan P. Parkin, Guanjie He   +3 more
wiley   +1 more source

Neonatal intensive care units as a driver and reservoir of invasive infections: an example of the emerging Staphylococcus capitis multidrug-resistant NRCS-A clone

International Journal of Infectious Diseases
Introduction: Healthcare environments have been identified as a significant source of multidrug-resistant bacterial infections, particularly, in vulnerable patients such as very-low-birth-weight preterm infants.
Dr Yu Wan, Dr Elita Jauneikaite, Linxi Gao, Dr Bruno Pichon, Dr Ginny Moore, Dr Colin S Brown, Dr Alicia Demirjian, Dr Derren Ready   +7 more
doaj   +1 more source

Engineering Human Donor Derived Germinal Center‐Like Organoids (GCLOs) for Studying Immune Response to Vaccination

Advanced Science, EarlyView.
We bioengineered a new approach methodology of generating Germinal Center Organoids that self‐organize from human blood‐derived immune cells. These immune organoids reproduce key features of humoral immunity, IgG production, and plasmablast emergence.
Bhumi Suthar, Carlos Gomez, Giancarlo Asencio, Suresh Pallikkuth, Ashutosh Agarwal   +4 more
wiley   +1 more source

Designing and Prototyping of a Portable Cradle Infant Warmer

Rwanda Medical Journal
INTRODUCTION: Neonatal hypothermia is a leading cause of mortality among premature and low-birth-weight infants, particularly in low-resource settings like Rwanda, where access to conventional thermoregulation devices such as incubators and radiant ...
Dushimimana et al.
doaj   +1 more source

Improving Newborn Health in Countries Exposed to Political Violence: An Assessment of the Availability, Accessibility, and Distribution of Neonatal Health Services at Palestinian Hospitals

Journal of Multidisciplinary Healthcare, 2020
Salwa Massad,1 Marina Tucktuck,2 Ranin Dar Khawaja,3,4 Hadil Dalloul,1 Khalid Abu Saman,1 Rand Salman,1 Rawan Kafri,1 Hatem Khammash5,6 1Research Unit, Palestinian National Institute of Public Health, Ramallah, Palestine; 2School of Medicine, St.
Massad S, Tucktuck M, Dar Khawaja R, Dalloul H, Abu Saman K, Salman R, Kafri R, Khammash H   +7 more
doaj  

Mapping Steroidogenic Perturbations Under Endocrine Disruptor Mixtures Across Demographic Subgroups: Structural and Metabolomic Insights

Advanced Science, EarlyView.
Population‐scale EDC–hormone association mapping among 4255 participants across demographic subgroups identifies phthalate metabolites as the most consistent signals associated with lower testosterone‐related markers in males. Integrative mechanistic validation prioritizes MCPP as a key phthalate metabolite linked to CYP17A1‐centered disruption of ...
Yanling Chen, Lei Huang, Yingtong Jiang, Guohong Zhao, Mengyuan Zhu, Xiulian Lu, Lang Lang, Akinpelumi Oluwatobiloba Esther, Longhao Fan, Yuqi Jiang, Chang Sun, Xiaoling Zhang, Kun Zhou, Xiaoming Ji, Minjian Chen   +14 more
wiley   +1 more source

Factors Influencing the Implementation of Infant Warming Devices Among Healthcare Workers in Malawian Hospitals

Global Pediatric Health
Objectives . Preterm infants are at risk of hypothermia. This study described the available infant warming devices (IWDs) and explored the barriers and facilitators to their implementation in neonates in Malawi. Methods .
Alinane Linda Nyondo-Mipando PhD, Mai-Lei Woo Kinshella MSc, Sangwani Salimu MPH, Brandina Chiwaya NMT, Felix Chikoti NMT, Lusungu Chirambo, Ephrida Mwaungulu NMT, Mwai Banda BSc, Tamanda Hiwa MMed, Marianne Vidler PhD, Elizabeth M. Molyneux MD, Queen Dube PhD, Joseph Mfutso-Bengo PhD, David M. Goldfarb PhD, Kondwani Kawaza MMed   +14 more
doaj   +1 more source

Selected Abstracts of the 9th International Workshop on Neonatology; Cagliari (Italy); October 23-26, 2013

Journal of Pediatric and Neonatal Individualized Medicine, 2013
Selected Abstracts of the 9th International Workshop on Neonatology • LEARNED LESSONS, CHANGING PRACTICE AND CUTTING-EDGE RESEARCH • Cagliari (Italy) • October 23rd-26th 2013 The Workshop has been organized on behalf of Union of European Neonatal and ...
--- Various Authors
doaj   +1 more source

Ubiquitination of ACSL4 by Parkin Suppresses Ferroptosis and Rescues Glucocorticoid‐Induced Bone Loss

Advanced Science, EarlyView.
GCs reduce Parkin, leading to ACSL4 accumulation and PUFA‐phospholipid‐driven ferroptosis in BMSCs, which impairs osteogenesis and promotes adipogenesis, causing GIOP. Parkin restoration (via OE‐Parkin or Parkin‐LNP@DSS6) ubiquitinates and degrades ACSL4, inhibiting ferroptosis, rescuing bone formation, and rescues GIOP bone loss.
Li‐jiang Han, Jian‐sen Miao, Yi‐feng Shi, Yi‐ting Tu, Yu‐zhe Lin, Lin‐Jie Chen, Bing‐hao Lin, Hua‐lin Li, Xuan‐qi Zheng, Hong‐qiang Wu, Hai‐xiao Liu, Lei Yang, Ai‐min Wu, Zhen Lin, Jian Xiao, Gang Zheng, Chen Jin   +16 more
wiley   +1 more source