Results 141 to 150 of about 7,519 (213)

Cellular activity upregulation of the thermolabile p53 cancer mutant Y220C by small molecule indazole derivatives. [PDF]

Cell Death Discov
Khadiullina R, Chasov V, Gilyazova E, Davletshin D, Mirgayazova R, Mingaleeva R, Stephenson Clarke JR, Baud MG, Bulatov E.   +8 more
europepmc   +1 more source

Novel Substituted Indazoles as Small Molecule-Based Inhibitors of KRAS Proteins. [PDF]

ACS Med Chem Lett
Rong J, Liang SH.
europepmc   +1 more source

Molecular Dynamics-Guided Design and Chemoproteomic Profiling of Covalent Kinase Activity Probes. [PDF]

J Am Chem Soc
Chakraborty P, Carlos A, Thomas T, Ghaby K, Fathi S, Sharma M, Nguyen NK, Farmwald M, Blachowicz L, Alcyone E, Harter K, Yu S, Pillai KS, Roux B, Moellering RE.   +14 more
europepmc   +1 more source

Phototransposition of Indazoles to Benzimidazoles: Tautomer-Dependent Reactivity, Wavelength Dependence, and Continuous Flow Studies. [PDF]

Angew Chem Int Ed Engl
Bartholomew GL, Kim SF, Oyamada Y, Sbordone F, Carroll JA, Jurczyk JE, Yeung CS, Barner-Kowollik C, Sarpong R.   +8 more
europepmc   +1 more source

Synthetic Cannabinoids: Metabolism, Biomarkers of Exposure and Advanced Analytical Strategies in Forensic and Clinical Toxicology. [PDF]

Toxics
Gomes TM, Guedes de Pinho P, Nunes I, Câmara JS.   +3 more
europepmc   +1 more source

Towards better outcomes for epidermal growth factor receptor L858R+ lung cancer patients: mutant-selective allosteric inhibitors and the potential for double-drugging. [PDF]

Philos Trans R Soc Lond B Biol Sci
Eck MJ, Scott DA.
europepmc   +1 more source

Targeting Neuroinflammation and Cognitive Decline: First-in-Class Dual Butyrylcholinesterase and p38α Mitogen-Activated Protein Kinase Inhibitors. [PDF]

J Med Chem
Ferjančič Benetik S, Proj M, Knez D, Košak U, Meden A, Krajšek K, Pišlar A, Horvat S, Švajger U, Tešić N, Pulkrabkova L, Soukup O, Skarka A, Andrys R, Brazzolotto X, Igert A, Nachon F, Dias J, Detka J, Gdula-Argasińska J, Wyska E, Szafarz M, Manik A, Płachtij N, Musílek K, Sałat K, Obreza A, Gobec S.   +27 more
europepmc   +1 more source

Novel Indazole Propionic Acid Derivatives as AMPK Activators. [PDF]

ACS Med Chem Lett
Rong J, Liang SH.
europepmc   +1 more source

Impact of Indazole Scaffold as Antibacterial and Antifungal Agent

Current Topics in Medicinal Chemistry, 2022
: Heterocycles consisting of nitrogen atom, Indazole, is a pungent, biological, heterocyclic, bicyclic compounds possessing electron rich portions. Indazole composed of two nitrogen atoms put under the azoles family, further called as isoindazolone.
Sridevi Chigurupati, Sitansu Sekhar Nanda, Dong Kee Yi   +2 more
exaly   +1 more source