Results 141 to 150 of about 71,108 (308)

On the Destruction and Humanitarianisation of the Health System in Gaza and the Need for a Biopolitical Bioethics

open access: yesBioethics, EarlyView.
ABSTRACT This paper examines Israel's destruction and ‘humanitarianisation’ of Palestinian health systems, arguing that this should be understood as an instance of ‘necropolitics,’ as conceived by Achille Mbembe. We review the extensive, long‐term destruction of health systems in Palestine before 7 October 2023 and the catastrophic acceleration of that
Mohammad Salaymeh   +2 more
wiley   +1 more source

Targeting protein–protein interactions with reversible covalent modalities: Non‐cysteine chemistries

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Protein–protein interactions (PPIs) are central to diverse cellular functions, and represent a rapidly expanding class of therapeutic targets. Advancements in covalent drug design have enabled small‐molecule drugs to overcome challenges associated with engaging these targets, such as limited durations of action and difficult‐to‐drug (expansive,
Ruchira Basu, Steven Fletcher
wiley   +1 more source

The division of labour between the Basque articles in the indefinite domain

open access: yesFontes Linguae Vasconum
The usage of the Basque definite and indefinite articles differs significantly from their Romance counterparts. While the definite article is used as a default article for NPs without another determiner, the exact function of the indefinite article in ...
Silvie Strauss
doaj   +1 more source

The indefinite closed world assumption

open access: yes, 1994
The inadequacy of the Closed World Assumption in dealing with indefinite information has led to the Generalised Closed World Assumption and the Extended Generalised Closed World Assumption. However, these approaches have serious shortcomings.
Williams, Howard, Chen, G., Kong, Q.
core  

Progressively Projected Newton's Method

open access: yesComputer Graphics Forum, EarlyView.
Abstract Newton's Method is widely used to find the solution of complex non‐linear simulation problems. To guarantee a descent direction, it is common practice to clamp the negative eigenvalues of each element Hessian prior to assembly—a strategy known as Projected Newton (PN)—but this perturbation often hinders convergence.
J. A. Fernández‐Fernández   +2 more
wiley   +1 more source

Register‐Efficient Linear‐Time Evaluation in the Bernstein Basis

open access: yesComputer Graphics Forum, EarlyView.
Abstract We investigate the evaluation of points and derivatives of Bézier curves and surfaces on modern architectures, focusing on performance and guided by numerical error bounds. While the de Casteljau algorithm remains the reference for numerical robustness, its linear working‐set size imposes substantial register pressure on GPUs.
Gábor Valasek, Anna Lili Horváth
wiley   +1 more source

The Wire Is Not the Territory: Understanding Representational Drift in Olfaction With Dynamical Systems Theory

open access: yesTopics in Cognitive Science, EarlyView., 2023
Abstract Representational drift is a phenomenon of increasing interest in the cognitive and neural sciences. While investigations are ongoing for other sensory cortices, recent research has demonstrated the pervasiveness in which it occurs in the piriform cortex for olfaction.
Ann‐Sophie Barwich   +1 more
wiley   +1 more source

Foundations of Indefinite Constraint Databases

open access: yes, 1994
We lay the foundations of a theory of constraint databases with indefinite information based on the relational model. We develop the scheme of indefinite L-constraint databases where L, the parameter, is a first-order constraint language.
Manolis Koubarakis
core  

Impact of Sleeve Gastrectomy Versus Intensive Lifestyle Modifications With Obesity Management Medications on BMI Trajectory and Target Attainment: A Prospective Matched Cohort Study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To compare sleeve gastrectomy (SG) with intensive lifestyle modification combined with obesity management medications (ILM/OMMs) in adults with severe obesity, focusing on BMI trajectory, time to achieving clinically meaningful weight loss, and metabolic outcomes in a real‐world clinical setting.
Maria Francesca Russo   +7 more
wiley   +1 more source

Spanish stock returns, growth, and inflation, 1900–2020

open access: yesThe Economic History Review, EarlyView.
Abstract This paper studies equity returns in the Madrid Stock Exchange and their connections with the macroeconomy from the emergence of a stock market around 1900 to its ‘big bang’ at the turn of the twenty‐first century. Using high‐quality data from primary sources and the methodology of the modern IBEX35 (published since 1987), we constructed an ...
Stefano Battilossi   +2 more
wiley   +1 more source

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