Results 31 to 40 of about 105,918 (288)

Lack of Association between LCT_rs140433552*CA>del Indel Polymorphism and Lactose Intolerance in a Southern Brazilian Population

open access: yesLifestyle Genomics, 2020
Background/Aims: Polymorphisms in the enhancer of the lactase gene (LCT) are strongly associated with lactase persistence, but not always predictive of the phenotype.
Luana Caroline Oliveira   +3 more
doaj   +1 more source

Identification of Vibrio cholerae Strains of the «Haitian» Group by PCR Based on INDEL-Typing

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2020
The aim of the work was to find a genetic INDEL-marker of the Haitian group of Vibrio cholerae strains, what allow carrying out their identification by means PCR.Materials and methods. For searching INDEL-markers we used the data from GenBank database on
Alexey S. Vodop’yanov   +3 more
doaj   +1 more source

An Efficient Workflow for Screening and Stabilizing CRISPR/Cas9-Mediated Mutant Lines in Bombyx mori

open access: yesMethods and Protocols, 2020
The domestic silkworm Bombyx mori is extensively studied as a model organism for lepidopteran genetics and has an economic value in silk production. Silkworms also have applications in biomedical and cosmetic industries, and the production of mutant B ...
Daniel Brady   +3 more
doaj   +1 more source

Structural Analysis of Polarizing Indels Argues the Root of the Tree of Life is Near the Chloroflexi [PDF]

open access: yes, 2009
Determining which branches of the tree of life have derived features narrows down the possible location of the root. Currently the polarization of indels done by Lake _et al_.^1-5^ and the polarizing transitions of Cavalier-Smith^6^ arrive at ...
Philip E. Bourne, Ruben E. Valas
core   +2 more sources

Organellar inheritance in the green lineage: insights from Ostreococcus tauri [PDF]

open access: yes, 2013
Along the green lineage (Chlorophyta and Streptophyta), mitochondria and chloroplast are mainly uniparentally transmitted and their evolution is thus clonal. The mode of organellar inheritance in their ancestor is less certain.
Adam Eyre-Walker   +56 more
core   +1 more source

Genetic Diversity of Botrytis cinerea Revealed by Multilocus Sequencing, and Identification of B. cinerea Populations Showing Genetic Isolation and Distinct Host Adaptation

open access: yesFrontiers in Plant Science, 2021
Botrytis cinerea is a world-wide occurring plant pathogen, causing pre- and post-harvest gray mold rot on a large number of fruit, vegetable, and flower crops. B.
Cecilia Plesken   +7 more
doaj   +1 more source

Dynamics of transcription factor binding site evolution [PDF]

open access: yes, 2015
Evolution of gene regulation is crucial for our understanding of the phenotypic differences between species, populations and individuals. Sequence-specific binding of transcription factors to the regulatory regions on the DNA is a key regulatory ...
Barton, Nicholas H.   +3 more
core   +6 more sources

Targeted genome modifications in soybean with CRISPR/Cas9 [PDF]

open access: yes, 2015
Background: The ability to selectively alter genomic DNA sequences in vivo is a powerful tool for basic and applied research. The CRISPR/Cas9 system precisely mutates DNA sequences in a number of organisms.
Jacobs, Thomas   +3 more
core   +2 more sources

Tumor mutational and indel burden: a systematic pan-cancer evaluation as prognostic biomarkers.

open access: yesAnnals of Translational Medicine, 2019
Background Tumor mutational burden (TMB) has been widely studied as a predictive biomarker of response to immune checkpoint inhibitors (ICIs). Besides, evidence suggests frameshift indels are a highly immunogenic mutational class and thus a potentially ...
Hao-xiang Wu   +11 more
semanticscholar   +1 more source

Removing reference bias and improving indel calling in ancient DNA data analysis by mapping to a sequence variation graph

open access: yesGenome Biology, 2020
During the last decade, the analysis of ancient DNA (aDNA) sequence has become a powerful tool for the study of past human populations. However, the degraded nature of aDNA means that aDNA molecules are short and frequently mutated by post-mortem ...
Rui Martiniano   +4 more
semanticscholar   +1 more source

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