Results 31 to 40 of about 105,918 (288)
Background/Aims: Polymorphisms in the enhancer of the lactase gene (LCT) are strongly associated with lactase persistence, but not always predictive of the phenotype.
Luana Caroline Oliveira +3 more
doaj +1 more source
Identification of Vibrio cholerae Strains of the «Haitian» Group by PCR Based on INDEL-Typing
The aim of the work was to find a genetic INDEL-marker of the Haitian group of Vibrio cholerae strains, what allow carrying out their identification by means PCR.Materials and methods. For searching INDEL-markers we used the data from GenBank database on
Alexey S. Vodop’yanov +3 more
doaj +1 more source
An Efficient Workflow for Screening and Stabilizing CRISPR/Cas9-Mediated Mutant Lines in Bombyx mori
The domestic silkworm Bombyx mori is extensively studied as a model organism for lepidopteran genetics and has an economic value in silk production. Silkworms also have applications in biomedical and cosmetic industries, and the production of mutant B ...
Daniel Brady +3 more
doaj +1 more source
Structural Analysis of Polarizing Indels Argues the Root of the Tree of Life is Near the Chloroflexi [PDF]
Determining which branches of the tree of life have derived features narrows down the possible location of the root. Currently the polarization of indels done by Lake _et al_.^1-5^ and the polarizing transitions of Cavalier-Smith^6^ arrive at ...
Philip E. Bourne, Ruben E. Valas
core +2 more sources
Organellar inheritance in the green lineage: insights from Ostreococcus tauri [PDF]
Along the green lineage (Chlorophyta and Streptophyta), mitochondria and chloroplast are mainly uniparentally transmitted and their evolution is thus clonal. The mode of organellar inheritance in their ancestor is less certain.
Adam Eyre-Walker +56 more
core +1 more source
Botrytis cinerea is a world-wide occurring plant pathogen, causing pre- and post-harvest gray mold rot on a large number of fruit, vegetable, and flower crops. B.
Cecilia Plesken +7 more
doaj +1 more source
Dynamics of transcription factor binding site evolution [PDF]
Evolution of gene regulation is crucial for our understanding of the phenotypic differences between species, populations and individuals. Sequence-specific binding of transcription factors to the regulatory regions on the DNA is a key regulatory ...
Barton, Nicholas H. +3 more
core +6 more sources
Targeted genome modifications in soybean with CRISPR/Cas9 [PDF]
Background: The ability to selectively alter genomic DNA sequences in vivo is a powerful tool for basic and applied research. The CRISPR/Cas9 system precisely mutates DNA sequences in a number of organisms.
Jacobs, Thomas +3 more
core +2 more sources
Tumor mutational and indel burden: a systematic pan-cancer evaluation as prognostic biomarkers.
Background Tumor mutational burden (TMB) has been widely studied as a predictive biomarker of response to immune checkpoint inhibitors (ICIs). Besides, evidence suggests frameshift indels are a highly immunogenic mutational class and thus a potentially ...
Hao-xiang Wu +11 more
semanticscholar +1 more source
During the last decade, the analysis of ancient DNA (aDNA) sequence has become a powerful tool for the study of past human populations. However, the degraded nature of aDNA means that aDNA molecules are short and frequently mutated by post-mortem ...
Rui Martiniano +4 more
semanticscholar +1 more source

