Results 221 to 230 of about 2,862,918 (376)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Handgrip Strength, Depression, Dementia, Cognitive Function, and Their Predictive Effect on Functional Independence in Older Adults. [PDF]

open access: yesMedicina (Kaunas)
Campos-Gutiérrez JA   +8 more
europepmc   +1 more source

On the concept of rate-independence [PDF]

open access: bronze, 1968
D. R. J. Owen, William O. Williams
openalex   +1 more source

Independent Commissioners: How Independent?

open access: yesjhbbc
Companies are managed by directors whose decisions and actions are overseen by a board of commissioners, which includes both commissioners and independent commissioners. An independent commissioner is a party that shares no relationships with the company's directors or the company itself.
openaire   +2 more sources

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Moderation Effect of Handgrip Strength on Cognition and Functional Independence Associations in Adults Over 90 Years. [PDF]

open access: yesJ Cachexia Sarcopenia Muscle
Sáez de Asteasu ML   +7 more
europepmc   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu   +11 more
wiley   +1 more source

Time course for acquiring toileting independence in patients with subacute stroke: a prospective cohort study. [PDF]

open access: yesJ Rehabil Med
Kitamura S   +10 more
europepmc   +1 more source

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