Results 311 to 320 of about 2,862,918 (376)

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Impact of sarcopenia on gait independence in older orthopaedic patients: a comparison of 2 diagnostic algorithms. [PDF]

J Rehabil Med
Ikemoto T, Tokuda M, Morikawa Y, Kuroda K, Nakayama N, Terada N, Niina M, Matsumoto D.   +7 more
europepmc   +1 more source

The Erosion of Colonial Trade Linkages after Independence

, 2008
K. Head, T. Mayer, J. Ries
semanticscholar   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Antigravity muscle density on computed tomography and health-related independence in normal weight patients with chronic obstructive pulmonary disease. [PDF]

Respir Res
Terada S, Tanabe N, Maetani T, Shiraishi Y, Terada K, Shima H, Oguma T, Sakamoto R, Kanasaki M, Masuda I, Sato A, Sato S, Hirai T.   +12 more
europepmc   +1 more source

Independence of Galvanic Skin Response Amplitude and Sweat Production

, 1964
Robert Edelberg
openalex   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

External validation of the MR PREDICTS@24H model: predicting functional outcome after endovascular treatment in stroke. [PDF]

BMJ Neurol Open
Tas J, Sick CC, Kulyk C, Ianosi BA, Spiandorello P, Vosko MR, Sonnberger M, Bergmann M, Helbok R.   +8 more
europepmc   +1 more source

Small modifier, big decision: switching to SUMO mode adds weight to cancer stemness in mammary tumors

Molecular Oncology, EarlyView.
Inhibition of protein SUMOylation has been shown to block tumorigenesis; however, the specific mechanisms by which SUMOylation controls the tumor‐initiating capacities remain elusive. Li et al. describe the role of Etv1 SUMOylation in cancer stem cells using mouse models of mammary gland tumorigenesis.
Veronika Yevdokimova, Yannick D. Benoit
wiley   +1 more source

Activities of daily living limitations in relation to the presence of pain in community-dwelling older adults. [PDF]

Sci Rep
Balicki P, Sołtysik BK, Borowiak E, Kostka T, Kostka J.   +4 more
europepmc   +1 more source