Results 251 to 260 of about 1,974,122 (287)
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Development and Statistical Validation of a Machine Learning Model for Predicting Functional Outcomes at Discharge after Bipolar Hip Arthroplasty. [PDF]
Kaneoka T +3 more
europepmc +1 more source
Correction: Antigravity muscle density on computed tomography and health-related independence in normal weight patients with chronic obstructive pulmonary disease. [PDF]
Terada S +12 more
europepmc +1 more source
Calcineurin inhibitor and eltrombopag combination for acquired aplastic anemia: results from a large national database. [PDF]
Stempel JM +5 more
europepmc +1 more source
Efficacy and safety of plasma exchange for crescentic and mixed classes of ANCA-associated glomerulonephritis with renal insufficiency. [PDF]
Yao Z, Wang P, Gao Y, Zhang P.
europepmc +1 more source

