Results 121 to 130 of about 580 (262)

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

Advanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu, Xinyu Sun, Wanxia Ma, Jianming Yang, Xuan Sun, Lisong Zhang, Yumeng Liu, Tianshu Ren, Qi Wang, Jingyu Wang, Xiao Li, Xianping Peng, Liu Yang, Junqiang Lv, Zhi Yao, Zhi‐Song Zhang, Quan Wang   +16 more
wiley   +1 more source

Studying of independency of a central bank through the realization of the investing and innovation strategy

, 2006
Проблема незалежності центрального банку держави досить гостро стоїть сьогодні перед урядами таких високорозвинутих країн, як США, Франція, Німеччина та Великобританія.
Процик, Т.В.
core  

Long-term efficacy of an optimized online gambling self-exclusion procedure with extended suspension of commercial solicitations: a randomized controlled trial. [PDF]

Harm Reduct J
von Hammerstein C, Benyamina A, Luquiens A.   +2 more
europepmc   +1 more source

Understanding Covid-19 Mobility Through Human Capital: A Unified Causal Framework. [PDF]

Comput Econ, 2023
Bilgel F, Karahasan BC.
europepmc   +1 more source

Molecular Glue cc‐885 Inhibits VHL‐Deficient Clear Cell Renal Cell Carcinoma via ETS1 Degradation

Advanced Science, EarlyView.
VHL‐deficient kidney cancer lacks effective treatments. This study reveals that the molecular glue degrader cc‐885 hijacks the cellular recycling system to selectively destroy the oncogenic protein ETS1, effectively killing VHL‐mutant tumors. Combining CC‐885 with the approved drug belzutifan achieves powerful synergy, offering a promising new ...
Taowei Yang, Qihao Li, Kun Ye, Kezhi Liu, Mi Zhou, Minyu Chen, Lican Liao, Kangbo Huang, Zhu Wang, Qiong Deng, Jieyan Wang, Meiyu Jin, Xu Chen, Hui Liang, Jiaxing Zhang, Junhang Luo   +15 more
wiley   +1 more source

AEBP1-GLI1 pathway attenuates the FACT complex dependency of bladder cancer cell survival. [PDF]

Biochem Biophys Rep
Kurosu H, Yamada N, Nakamura R, Ito H, Ohnishi K, Inoko A, Riku M, Muramatsu T, Sassa N, Kasai K.   +9 more
europepmc   +1 more source

Full‐Body AI Agent: A Perspective on Multi‐Scale Collaborative AI for Systemic Biology and Precision Medicine

Advanced Science, EarlyView.
We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang, Jiajia Liu, Jianguo Wen, Yangyang Luo, Zhiwei Fan, Liren Yang, Xi Hu, Ruihan Luo, Yankai Yu, Sophia Li, Weiling Zhao, Xiaobo Zhou   +11 more
wiley   +1 more source

Configuration of strategy maps in public sector and an application

, 2010
Çalışmanın amacı, kamu sektörü ve merkez bankaları açısından stratejik yönetim sürecinde performans ölçümünün öneminin ve performans ölçüm süreçlerinin incelenmesi; elde edilen bilgiler ve merkez bankası uygulamalarından hareketle Türkiye Cumhuriyeti ...
Öztürk, Beytullah
core  

Functional improvements correlate with enhanced quality of life following mesenchymal stromal cell therapy in chronic spinal cord injury. [PDF]

Sci Rep
Jafar H, Jamali F, Al-Hattab D, Ammar A, Al-Hayali A, Sroji H, Al Shudifat A, El Adwan N, Awidi A.   +8 more
europepmc   +1 more source

Post-conflict development, reviewing the water sector in Somalia. [PDF]

Environ Dev Sustain, 2023
Mourad KA.
europepmc   +1 more source