Results 41 to 50 of about 580 (262)
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
, 2016 Central banks are the most efficient institutions for maintaining and sustaining their countries' economic stability. Through their policy instruments, central banks have many functions such as price stability, maintaining the value of national currency,
Güresçi E., Aktürk O.
core +1 more source
Effect of the lengths of multiple splitter plates on the flow past a bank of cylindrical tubes
, 2023 <p>A two-dimensional numerical study of the crossflow past a staggered cylindrical tube bank with multiple splitter plates attached behind the tube was performed.
Ilikan, Ayhan Nazmi
core +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
, 2007 Práce se zabývá nezávislostí centrálních bank, záběrem od právního postavení CB, aspektů nezávislosti, argumentů pro a proti vysoké míře nezávislosti, dále přehled studií zabývajích se nezávislostí CB až po politické vlivy na centrální ...
Böhm, Tomáš
core
Central Bank independence and supervision: theoretical and empirical support
, 2008 The aim of PHD is to work on τhe two functions of the ECB, monetary policy and prudential supervision. The innovation of this research lies in the fact that it gives a specific answer to the question whether ECB can implement both its functions or not ...
Δουγέκος, Θεοφάνης +1 more
core +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Bank Indonesia dalam Tata Pemerintahan Indonesia
, 2010 This research focuses on problems as follows: First, position and role of Bank Indonesia as a state body in Indonesia; Second, independency of central bank in performing its monetary function. This research is a juridical normative research using primary
Ismail, Maqdir
core
Institutional Resilience During War
, 2022 My research assesses why some formal service-delivery institutions are more resilient than others during wars; what role trust plays in institutional resilience and why some institutions are able to maintain donors’ support even in times of war while ...
Abdul Ghaffar, Jeehan
core +1 more source