Results 171 to 180 of about 16,633,437 (341)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

A PROBLEMATIC APPROACH TO THE ORGANIZATION OF INDEPENDENT WORK AS A MEANS OF IMPROVING THE QUALITY OF KNOWLEDGE OF STUDENTS OF THE PEDAGOGICAL UNIVERSITY

Освітній вимір, 2010
The article deals with the problem concerning self-directed independent activities at a teacher training higher educational establishment on the basis of a task approach as the means of improvement student s knowledge quality.
M.A. Slyusarenko
doaj  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

A Potent HER3 Monoclonal Antibody That Blocks Both Ligand-Dependent and -Independent Activities: Differential Impacts of PTEN Status on Tumor Response

Molecular Cancer Therapeutics, 2016
Zhan Xiao, R. Carrasco, Kevin P. Schifferli, Krista Kinneer, R. Tammali, Hong Chen, R. Rothstein, Leslie K Wetzel, Chunning Yang, P. Chowdhury, P. Tsui, P. Steiner, B. Jallal, R. Herbst, R. Hollingsworth, D. Tice   +15 more
semanticscholar   +1 more source

Suppression of FGFR3- and MYC-dependent oncogenesis by tubacin: association with HDAC6-dependent and independent activities. [PDF]

Oncotarget, 2018
Ota S, Zhou ZQ, Hurlin PJ.
europepmc   +1 more source

Economic observatory: proposal of a longitudinal study on the profile of (dis)employment in the Alto Tietê Region

, 2020
Regional economic data provide myriad possibilities for pursuing projects related to economic growth and development. Specifically, the Economic Observatory consists of the process of elaboration, capture, analysis and distribution of information related
Filenga, Douglas
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

ClpP-dependent and -independent activities encoded by the polycistronic clpK-encoding locus contribute to heat shock survival in Klebsiella pneumoniae.

Research in Microbiology, 2013
M. Bojer, C. Struve, H. Ingmer, K. Krogfelt   +3 more
semanticscholar   +1 more source

A mutant form of Dmc1 that bypasses the requirement for accessory protein Mei5-Sae3 reveals independent activities of Mei5-Sae3 and Rad51 in Dmc1 filament stability. [PDF]

PLoS Genet, 2019
Reitz D, Grubb J, Bishop DK.
europepmc   +1 more source

Institutional environment for financial provision of small agricultural business entities of Ukraine

, 2020
The purpose of the study is to assess the institutional environment and determine the need for financing small agricultural businesses in Ukraine in order to facilitate access to financial resources in accordance with the need.
Piven, Alyona, Sinenok, Ihor, Radchenko, Oksana, Vdovenko, Nataliia, Voskobiinyk, Solomiya   +4 more
core   +1 more source