Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Characterization of Strombolian events by using independent component analysis [PDF]
Nonlinear Processes in Geophysics, 2004 We apply Independent Component Analysis (ICA) to seismic signals recorded at Stromboli volcano. Firstly, we show how ICA works considering synthetic signals, which are generated by dynamical systems.
A. Ciaramella +9 more
doaj
An Independent Component Analysis Based Tool for Exploring Functional Connections in the Brain [PDF]
, 2007 This thesis describes the use of independent component analysis (ICA) as a measure of voxel similarity, which allows the user to find and view statistically independent maps of correlated voxel activity. The tool developed in this work uses a specialized
Rolfe, Sara
core
A study of principal component analysis applied to spatially distributed wind power [PDF]
, 2011 Multivariate dimension reduction schemes could be very useful in limiting the number of random statistical variables needed to represent distributed wind power spatial diversity in transmission integration studies.
Burke, Daniel J. +4 more
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Imaging haemodynamic changes related to seizures: comparison of EEG-based general linear model, independent component analysis of fMRI and intracranial EEG [PDF]
, 2010 Background: Simultaneous EEG-fMRI can reveal haemodynamic changes associated with epileptic activity which may contribute to understanding seizure onset and propagation. Methods: Nine of 83 patients with focal epilepsy undergoing pre-surgical evaluation
Laufs, H. +9 more
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Contribution to discussion: MegaProgram M&E, independent evaluation arrangement
, 2023 The paper has three components. The first section discusses the important features of evaluation science and of research for development. The second section discusses options for the Independent Evaluation Arrangements regarding independence, other key ...
CGIAR Independent Science and Partnership Council
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
A multivariate generalized independent factor GARCH model with an application to financial stock returns [PDF]
, 2008 We propose a new multivariate factor GARCH model, the GICA-GARCH model , where the data are assumed to be generated by a set of independent components (ICs).
García-Ferrer, Antonio +2 more
core +1 more source
Independent Component Analysis to Detect Clustered Microcalcification Breast Cancers
The Scientific World Journal, 2012 The presence of clustered microcalcifications is one of the earliest signs in breast cancer detection. Although there exist many studies broaching this problem, most of them are nonreproducible due to the use of proprietary image datasets. We use a known
R. Gallardo-Caballero +4 more
doaj +1 more source