Results 171 to 180 of about 28,681,192 (295)

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

The impact of Independent Component Analysis on TMS-evoked potentials: a within-subject comparison across motor and prefrontal areas. [PDF]

Clin Neurophysiol Pract
Oostra E, d'Angremont E, van Hattem T, Anand S, Schubert S, van den Heuvel OA, van der Werf YD.   +6 more
europepmc   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Noise Elimination of PD Signals by Independent Component Analysis

工程科学与技术, 2007
:Since the requirement of Independent Component Analysis (ICA) was multi-channels signals, the Empirical Mode Decomposition (EMD) was proposed to construct the multi channels signals and a new method of eliminating noises in partial discharge signals of ...
doaj  

Brain Network Patterns in Patients With Multiple System Atrophy: Spatial Independent Component Analysis Using FDG-PET Data. [PDF]

Neurology
Wang H, Wang B, Liao Y, Jin N, Kang Y, Wang X, Li J, Wu S, Zhong Y, Dou X, Yu C, Feng K, Zhang H, Tian M, Luo W.   +14 more
europepmc   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Impaired brain intrinsic connectivity in long COVID during cognitive exertion revealed by independent component analysis. [PDF]

Sci Rep
Barnden L, Baraniuk J, Inderyas M, Eaton-Fitch N, Marshall-Gradisnik S, Thapaliya K.   +5 more
europepmc   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source

Reliable Single-Trial Detection of Saccade-Related Lambda Responses with Independent Component Analysis. [PDF]

eNeuro
Suhaili ISB, Toth B, Nagy Z, Juhasz Z.
europepmc   +1 more source

Nonlinear independent component analysis for principled disentanglement in unsupervised deep learning. [PDF]

Patterns (N Y), 2023
Hyvärinen A, Khemakhem I, Morioka H.
europepmc   +1 more source