Results 221 to 230 of about 27,220,972 (292)

Structural and Biochemical Characterization of the Diaminopimelate Epimerase DapF From Pseudomonas aeruginosa PA14

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 12, Page 2002-2012, December 2026.
ABSTRACT The emergence of antibiotic resistance in bacteria is a major threat to global public health. To combat increasingly drug‐resistant bacteria like Pseudomonas aeruginosa , new targets for pharmaceuticals need to be explored. One such potential target for P.
Philipp Schneider, Claudia Hanko, Konrad Büssow, Stefan Schmelz, Wulf Blankenfeldt   +4 more
wiley   +1 more source

Integrating scanning X-ray scattering and fluorescence for multi-scale analysis of seed structure supported by machine learning tools. [PDF]

Plant Methods
Merten L, Lotze G, Ahmad M, Roosen-Runge F.   +3 more
europepmc   +1 more source

Selective modulation of NaV channel gating counteracts aberrant hyperexcitability and rescues motor function and survival in a model of spinal muscular atrophy

British Journal of Pharmacology, Volume 183, Issue 23, Page 6824-6846, December 2026.
Background and Purpose Spinal muscular atrophy (SMA) is a motor neuron disease caused by SMN1 gene loss, leading to reduced survival motor neuron (SMN) protein and progressive motor neuron degeneration. Although SMN‐restoring therapies improve outcomes, residual disease burden and non‐curative efficacy underscore the need for complementary treatments ...
Fernanda C. Cardoso, Jessica A. I. Muller, Yougang Zhang, Jean Giacomotto   +3 more
wiley   +1 more source

A hybrid PCA-ICA and multi-level feature scaling framework with bidirectional LSTM-GRU architecture improves multivariate time series forecasting accuracy. [PDF]

Sci Rep
Boddu Y, Manimaran A, Talabathula J, Sucharitha M.   +3 more
europepmc   +1 more source

Mapping Flood Exposure and Consequences in Caravan and Mobile‐Home Parks: A Scoping and Bibliometric Review

Journal of Flood Risk Management, Volume 19, Issue 4, December 2026.
ABSTRACT Caravan and mobile‐home parks combine tourism, housing and communal infrastructure but remain weakly represented in flood‐risk assessment and disaster appraisal. This review maps evidence on their flood exposure, vulnerability and consequences and develops a structured basis for sector‐specific appraisal.
Afshin Fouladi Semnan, Faiza Yasmeen, Guomin Zhang, Wendy Steele, Sujeeva Setunge, Tariq Maqsood   +5 more
wiley   +1 more source

Explainable EEG-based machine learning for early diagnosis of Alzheimer's disease and frontotemporal dementia. [PDF]

Sci Rep
Saeed F, Aldera S.
europepmc   +1 more source

Structure and Propagation of Mesoscale Cyclonic Eddies in the Brazil–Malvinas Confluence

International Journal of Climatology, Volume 46, Issue 13, 15 November 2026.
Between 1993 and 2022, 1386 cyclonic eddies were identified in the Brazil–Malvinas Confluence, one of the most energetic regions of the South Atlantic. While most eddies dissipated locally, a smaller number of individuals, more energetic, and longer lived propagated predominantly south‐westward and north‐eastward, driven by topographic constraints and ...
Rafaella Oliveira Santos, Ilson Carlos Almeida da Silveira, Fabricio Sanguinetti Cruz de Oliveira   +2 more
wiley   +1 more source

Sex-related differences in the cortico-thalamo-cerebellar circuit in patients with schizophrenia. [PDF]

Front Psychiatry
Zhang Y, Duan M, Yao D, Rodriguez-Labrada R, Luo C, He H.   +5 more
europepmc   +1 more source

Nucleoside‐Modified mRNA Encoding Alpha‐Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC‐Derived Cardiomyocytes

Advanced Science, Volume 13, Issue 61, 3 November 2026.
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem, Lea Oehlsen, Sedef Ersoy, Jia Li Ye, Natalie Weber, Elisa Mohr, Wilson Agyapong, Junqing Liu, Maximilian Fuchs, Ke Xiao, Christopher Jahn, Reto Eggenschwiler, Tobias Cantz, Julia Beimdiek, Falk F. R. Buettner, Theresia Kraft, Jan Hegermann, Ivonne J. Knorr, Lisa Ernst, Linda Feldbrügge, Resa Puffert, Kevin Schmidt, Christian Bär, Jeannine Hoepfner, Thomas Thum   +24 more
wiley   +1 more source

Classifying schizophrenia patients and healthy individuals: Whole brain SPECT functional connectivity using support vector machine classification. [PDF]

Neuroimage Rep
Harikumar A, Wardell J, Keator D, Amen D, Plis SM, Calhoun VD.   +5 more
europepmc   +1 more source