Results 91 to 100 of about 1,652,945 (232)
FEBS Open Bio, EarlyView.Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley +1 more source
True Parallel Graph Transformations: an Algebraic Approach Based on Weak Spans
, 2019 We address the problem of defining graph transformations by the simultaneous application of direct transformations even when these cannot be applied independently of each other.
de la Tour, Thierry Boy, Echahed, Rachid
core
A candidate for a background independent formulation of M theory
, 1999 A class of background independent membrane field theories are studied, and several properties are discovered which suggest that they may play a role in a background independent form of M theory.
A. Ashtekar +108 more
core +3 more sources
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Buletin Ilmiah Nagari Membangun, 2019 Gemala Sari village, located on the outermost island adjacent to Malaysia and the Indonesian island of Batam, holds a natural and exotic beauty. The challenging condition of access roads to the villages will add to the challenges of the natural tourist ...
Chelsy Yesicha +2 more
doaj +1 more source
Embedding the intrinsic relevance of vertices in network analysis: the case of centrality metrics
Scientific Reports, 2020 Complex network theory (CNT) is gaining a lot of attention in the scientific community, due to its capability to model and interpret an impressive number of natural and anthropic phenomena.
Orazio Giustolisi +2 more
doaj +1 more source
Quaternary matroids are vf-safe [PDF]
, 2014 Binary delta-matroids are closed under vertex flips, which consist of the natural operations of twist and loop complementation. In this note we provide an extension of this result from GF(2) to GF(4).
Brijder, Robert, Hoogeboom, Hendrik Jan
core
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Dissipation Layers in Rayleigh-B\'{e}nard Convection: A Unifying View
, 2013 Boundary layers play an important role in controlling convective heat transfer. Their nature varies considerably between different application areas characterized by different boundary conditions, which hampers a uniform treatment.
Hansen, U. +4 more
core +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source