Results 101 to 110 of about 12,784,680 (324)
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
INDEX AUTHOR AND SUBJECT VOL. 11 NO. 2 OCTOBER 2018
INDEX INDEX
doaj +1 more source
Background: Adolescent even though constituted a sizeable population, their health needs are not properly met with their life style and behavior in a way affects the health of future adults. The research was conducted to study the knowledge attitude and
V P Goswami, Shailesh Rai
doaj
Improving the Measurement of Scientific Success by Reporting a Self-Citation Index [PDF]
Justin W. Flatt +2 more
openalex +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
INDEX AUTHOR AND SUBJECT VOL. 11 NO. 1 APRIL 2018
INDEX INDEX
doaj +1 more source
Running of the scalar spectral index in bouncing cosmologies [PDF]
Jean-Luc Lehners, Edward Wilson-Ewing
openalex +1 more source
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Propagation of acoustic waves in a metamaterial with a refractive index of near zero [PDF]
Choon Mahn Park, Sang Hun Lee
openalex +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source

