Results 111 to 120 of about 723,859 (290)
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
IEEE Access, 2018 In this treatise, we present the concept of compressed-sensing (CS)-aided space-time shift keying index modulation (STSK-IM), where a virtual domain orthogonal frequency division multiplexing (OFDM) symbol is divided into Na-sized blocks, which carry K ...
Ibrahim A. Hemadeh +3 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
High performance OFDM with index modulation
Physical Communication, 2019 Abstract Orthogonal frequency division multiplexing (OFDM) with index modulation (OFDM-IM), which has been recently proposed as an alternative waveform to classical OFDM, generally achieves lower bit error rate compared to classical OFDM because it is more robust to bit errors by encoding the information in the location of the active subcarriers ...
Yusuf Acar, Todor Cooklev
openaire +3 more sources
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Analysis of Output Current Ripple of Three-phase PWM Inverter under Discontinuous Modulation Techniques [PDF]
, 2010 In this paper, an analysis of output current ripple of three-phase PWM inverters with discontinuous modulation is presented. The analytical expressions for discontinuous modulation injection signal are derived.
Dahono, Pekik Argo
core
Rectangular Differential OFDM with Index Modulation
2019 IEEE 89th Vehicular Technology Conference (VTC2019-Spring), 2019 Orthogonal Frequency Division Multiplexing (OFDM) with Index Modulation (OFDM-IM), which conveyed information bits via the activated indices and constellation symbols is a promising technique in the next wireless communications. In the OFDM-IM scheme, only part of subcarriers are activated to transmit information, the inactive subcarriers transmit zero
Xiao, Lixia +5 more
openaire +3 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source