Results 281 to 290 of about 5,997,708 (388)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

An Epsilon-Near-Zero-Based Nonlinear Platform for Ultrafast Re-Writable Holography. [PDF]

Nanophotonics
Alam MZ, Fickler R, Zhou Y, Giese E, Upham J, Boyd RW.   +5 more
europepmc   +1 more source

Intermodal Modulation Instability and Four-Wave Mixing in Graded-Index Few-Mode Fibers

, 2018
A. Bendahmane, R. Dupiol, Katarzyna Krupa, Alessandro Tonello, Julien Fatome, Marc Fabert, Bertrand Kibler, Thibaut Sylvestre, Frédéric Smektala, Vincent Couderc, S. Wabnitz, G. Millot   +11 more
openalex   +2 more sources

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Time-programmable coloration via 3D metastructures for optical encryption. [PDF]

Light Sci Appl
Zhao MZ, Hu ZY, Tao YH, Zhou ZX, He LJ, Tian ZN, Liu XQ, Chen QD, Tsai DP.   +8 more
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Acute Effects of Transcutaneous Tibial Nerve Stimulation on Autonomic Nervous System Activity in Healthy Volunteers: An Exploratory Study. [PDF]

Neurourol Urodyn
Muñoz JA, Basualto-Alarcón C, Del Camino MD, Leiva D, Gálvez P, García J, Asenjo G, León A, Soto J, Valdevenito JP.   +9 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Hybrid tungsten oxyselenide/graphene electrodes for near-lossless 2D semiconductor phase modulators. [PDF]

Light Sci Appl
Guo S, Lee SG, Gong X, Singh L, Yu R, Juperi ASB, Lim S, Yang Y, Huo J, Leong J, Liang C, Seung H, He Y, Rhodes D, Choi MS, Taniguchi T, Watanabe K, Chang W, Tay BK, Ranno L, Hu J, Wu Q, Ang LK, Sia JXB, Chae SH.   +24 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source