Results 81 to 90 of about 4,542,507 (296)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Index

open access: yes, 2023
Index Vol ...
Index
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Periodic index-modulated plasma waveguide

open access: yesOptics Express, 2009
We demonstrate a wire-obstructed cluster flow technique for making periodically modulated plasma waveguides in hydrogen, nitrogen, and argon with sharp, stable voids as short as 50 microm with a period as small as 200 microm. These gaps persist as the plasma expands for the full lifetime of the waveguide.
B D, Layer   +4 more
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

IMToolkit: An Open-Source Index Modulation Toolkit for Reproducible Research Based on Massively Parallel Algorithms

open access: yesIEEE Access, 2019
This paper presents a proposal of an open-source index modulation (IM) toolkit, which facilitates reproducible research and accelerates open innovation in IM studies.
Naoki Ishikawa
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

High performance OFDM with index modulation

open access: yesPhysical Communication, 2019
Abstract Orthogonal frequency division multiplexing (OFDM) with index modulation (OFDM-IM), which has been recently proposed as an alternative waveform to classical OFDM, generally achieves lower bit error rate compared to classical OFDM because it is more robust to bit errors by encoding the information in the location of the active subcarriers ...
Yusuf Acar, Todor Cooklev
openaire   +4 more sources

Enhanced Index Modulated OFDM Spread Spectrum

open access: yesIEEE Access, 2018
Index modulated OFDM spread spectrum (OFDM-IM-SS) is a recently proposed scheme, which transmits the additional bits (index bits) through the code domain.
Jun Li   +4 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

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