α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
EFFECTS OF THE PULP PREPARATION AND PAPERMAKING PROCESSES ON THE PROPERTIES of OCC FIBERS
BioResources, 2011 Changes of the pore structure of recycled fibers and the strength properties of papers produced by old corrugated container (OCC) recycled fibers were studied, after they were subjected to different stock preparation and papermaking processes.
Jinquan Wan +3 more
doaj
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
GTalign: spatial index-driven protein structure alignment, superposition, and search
Nature CommunicationsWith protein databases growing rapidly due to advances in structural and computational biology, the ability to accurately align and rapidly search protein structures has become essential for biological research. In response to the challenge posed by vast
Mindaugas Margelevičius
doaj +1 more source
Studying Focusing Properties of Graded Index Photonic Crystals Made of Material with Different Refractive Index [PDF]
Journal of Optoelectronical Nanostructures, 2017 In this paper we investigate focusing properties of graded index (GRIN) photonic crystal (PC) structures which are composed of different materials with different refractive indices. GRIN PC structure is constructed from air holes in dielectric background.
Nasrin Miri, Abdolrasoul Gharaati
doaj
Analysis of Development Performance Using a Development Index Based on Factor Analysis (Old Title- Constructing Multideminsional Indexes of Economic Structure and Development) [PDF]
Development involves changes in social, economic and institutional structures. Quantifying development requires a large array of variables with different characteristics often highly correlated.
D.S. Prasada Rao +3 more
core
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
High-Sensitivity Refractive Index Sensing Based on an SNPNS Composite Structure
PhotonicsIn this paper, we design and demonstrate an all-fiber-sensitive refractive index (RI) sensor based on the Mach–Zehnder interferometer (MZI). It is constructed by splicing two no-core fibers (NCFs) and a photonic crystal fiber (PCF) between two single ...
Di Wu, Jingwen Zhou, Xiang Yu, Yue Sun
doaj +1 more source
The partial adjustment factors of FTSE 100 stock index and stock index futures: The informational impact of electronic trading systems [PDF]
This paper examines the partial adjustment factors of FTSE 100 stock index and stock index futures. Using high frequency data since January 15, 1997 until March 17, 2000, it aims to assess the informational impact of the new electronic trading systems ...
Helder Sebastião
core
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source