Results 121 to 130 of about 24,024,082 (265)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Index 1977 [PDF]

open access: yes, 1977
This is the 1977 edition of the Index. The Index is written by student editors, and it is the college’s yearbook. It includes an annual record of events at Wooster.
Editors, Index
core  

Construction of evaluation index system of nursing human resources efficiency

open access: yesHuli yanjiu, 2019
Objective:To construct an evaluation index system of nursing human resources efficiency,in order to provide a basis for nursing managers to configure nursing human resources.Methods:Using the literature reading method and the interview method ...
翁艳翎   +3 more
doaj  

Evaluation of the Monitoring Capabilities of Remote Sensing Satellites for Maritime Moving Targets

open access: yesISPRS International Journal of Geo-Information
Although an Automatic Identification System (AIS) can be used to monitor trajectories, it has become a reality for remote sensing satellite clusters to monitor maritime moving targets.
Weiming Li   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Index 2007 [PDF]

open access: yes, 2007
This is the College of Wooster Index from 2007. The sections of the Index include Student Life, Organizations, Academics, Greek Life, Sports, and Seniors. At the end of the Index, there is a section dedicated to President R.
Editors, Index
core  

Preliminary construction of evaluation index system of nursing case teaching

open access: yesHuli yanjiu, 2019
Objective:To construct the evaluation index system of nursing case teaching,and to provide scientific basis for objective evaluation of the effect of case teaching.Methods:By Delphi method,28 experts who met the selection criteria were consulted by three
刘爱梅   +3 more
doaj  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Changes in Relative Consumer Prices and the Substitution Bias of the Laspeyres Price Index - Ireland, 1985-2001 [PDF]

open access: yes
This paper shows that Irish relative consumer prices have changed significantly, 1985- 2001, at the ten commodity-group level. A “true” cost-of-living index is derived from Madden’s (1993) parameter estimates for an Almost Ideal Demand System.
R. A. Somerville
core  

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