Results 151 to 160 of about 2,505,256 (301)

The development and validation of an estuarine health index using fish community characteristics

open access: yes, 2010
The overall aim of this thesis was to develop an approach for constructing and validating a fish-based, multimetric index for assessing the ecological health of estuaries in south-western Australia, and to apply that approach to the large Swan Estuary ...
Hallett, Christopher Sean
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Building Up a Real Sector Business Confidence Index for Turkey [PDF]

open access: yes
The two major aims of this study are, firstly, to receive valuable insight into the Business Tendency Survey of the Central Bank of the Republic of Turkey and, secondly, to construct a real sector confidence index by using the questions of the Business ...
Turknur Hamsici, Ece Oral, Dilara Ece
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

A Leading Index for the Colombian Economic Activity [PDF]

open access: yes
In this paper,we propose a methodology for calculating a leading index of the economic activity based on a modification of Stock and Watson's (1989, 1991, 1992) approach.
Luis Fernando Melo   +2 more
core  

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