Results 61 to 70 of about 1,357,593 (362)

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

“That’s What It Felt Like, ‘You’re Pathetic’”: Creaky voice, Affective Stance, and Authentication in the Speech of Lady Gaga

open access: yesLifespans and Styles, 2017
This paper contributes to research on the social meaning of creaky voice in American English by offering an intraspeaker analysis of the speech of Lady Gaga, an American pop star.
Lewis Esposito
doaj   +1 more source

Bearing Witness in Analog and Digital Witness Films: Ethical Aesthetics in Shoah [1985] and Waltz with Bashir [2008]

open access: yesGenealogy, 2022
In the ongoing and passionate debates over the digitalization of visual media, many questions about the ontology or materiality of the new digital image have been raised.
Louis Levi Breitsohl
doaj   +1 more source

A Pluggable Learned Index Method via Sampling and Gap Insertion [PDF]

open access: yesarXiv, 2021
Database indexes facilitate data retrieval and benefit broad applications in real-world systems. Recently, a new family of index, named learned index, is proposed to learn hidden yet useful data distribution and incorporate such information into the learning of indexes, which leads to promising performance improvements.
arxiv  

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Reading Qualitative Social Research Interculturally: The Reflection of Self-interpretation in the Act of Interpersonal Understanding (Fremdverstehen)

open access: yesForum: Qualitative Social Research, 2009
In this contribution, I attempt to justify the following two assumptions: Firstly, that intercultural communication is, at its heart, the communicative paradigm of qualitative interview-based research; and secondly that, vice versa, qualitative interview-
Jan Kruse
doaj  

Indexicality or Technological Intermediate? Moving Image Representation, Materiality, and the Real

open access: yesActa Universitatis Sapientiae: Film and Media Studies, 2016
Drawing on the application of C. S. Peirce’s notion of indexicality, this paper argues that iterative imaging technologies modulate the manner in which moving images represent reality and determine how they are traced back to that referent.
Verdon James
doaj   +1 more source

Being in the world

open access: yesSign Systems Studies, 2015
This essay addresses a question raised by Helmut Pape: “What logical, semiotical and mental structure does our consciousness have to have in order to establish the proper link between perception, thought and propositional content expressed by indicators?”
Nathan Houser
doaj   +1 more source

______ is Necessary for Interpreting a Proposition [PDF]

open access: yes, 2019
In Natural propositions (2014), Stjernfelt contends that the interpretation of a proposition or dicisign requires the joint action of two kinds of signs. A proposition must contain a sign that conveys a general quality.
Champagne, Marc
core  

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

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