Results 71 to 80 of about 1,355,032 (346)

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Thinking Complexity with Harrison White: Towards Social Emergence via Indexical Language

open access: yesSociologica
Harrison C. White, a founding giant of the relational turn in Sociology, has left us a monumental model of social emergence based on the interplay of three primitives (identity, control, switching) and two principles (self-similarity, dispersion) of ...
Jorge Fontdevila
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Toda mi posesión está expropiada: supervivencia y subjetividad a partir de Aliento de Óscar Muñoz

open access: yesHart, 2017
This paper explores the intimacy between the work of mourning and the structure of subjectivity in light of the artistic reformulation of specularity that is displayed in Muñoz’s installation, Aliento. Following Jean-Luc Nancy’s ideas on the way in which
Juan Diego Pérez Moreno
doaj   +1 more source

Social spatialization and everyday life [PDF]

open access: yes, 2007
This editorial introduction discusses the problematic ‘demonology’ of spatial analyses that attempt to understand the logic of the social in terms of subject-based origins.
Loon, J van
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Entre perception et praxis : à quoi la notion d’affordance en discours peut-elle bien pourvoir ?

open access: yesCorela, 2019
Taken in an all-encompassing sense (as initiated by Werner, 1926), the notion of affordance allows us to think as a first approximation our perceptual relation to objects and especially to what we make of this relation as subjects.
Laurent Fauré
doaj   +1 more source

ESSENTIAL PROPERTIES OF LANGUAGE FROM THE POINT OF VIEW OF AUTOPOIESIS [PDF]

open access: yes, 2004
The structuralist heritage in linguistics continues to obscure the essential properties of natural language as an empirical phenomenon. It is argued that the new framework of autopoiesis possesses a greater explanatory power, as it assumes the ...
Kravchenko, Prof. A.V.
core  

High altitude climbers as ethnomethodologists making sense of cognitive dissonance: ethnographic insights from an attempt to scale Mt Everest [PDF]

open access: yes, 2008
This ethnographic study examined how a group of high altitude climbers (N = 6)drew on ethnomethodological principles (the documentary method of interpretation, reflexivity, indexicality, and membership) to interpret their experiences of cognitive ...
Allen-Collinson, Jacquelyn   +2 more
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

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