Results 31 to 40 of about 119,163 (257)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Relations between indexing policy and language policy
, 2023 Esta pesquisa discute as primeiras aproximações entre a política de indexação e a política linguística. Tem-se como objetivo analisar as políticas de indexação de unidades de informação para destacar aspectos implícitos e explícitos de uma política linguística.
Andrade da Fonseca, Luciana Di Paula +3 more
openaire +1 more source
Fishing in the Stream: Similarity Search over Endless Data
, 2017 Similarity search is the task of retrieving data items that are similar to a given query. In this paper, we introduce the time-sensitive notion of similarity search over endless data-streams (SSDS), which takes into account data quality and temporal ...
Carmel, David +2 more
core +1 more source
Mentorship program to elevate journal quality and rankings in Indonesia: a case study [PDF]
Science EditingThis article explores the best practices of mentorship programs in all journals at Universitas Airlangga. The university has established a journal mentoring team, as mandated by the rector’s regulation, which is responsible for guiding journals through ...
Ferry Efendi +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Accessibility, language, discipline, and indexing status of university journals that use Open Journal Systems in Indonesia: a case study [PDF]
Science EditingThis case study examines the characteristics of university journals in Indonesia on the country’s most used platform, Open Journal Systems (OJS), following a decade of rapid growth in scholarly publishing.
Maria Lamury, John Willinsky
doaj +1 more source
the policy model of cyberspace filtering in Islamic Republic of IRAN [PDF]
مطالعات رسانههای نوین, 2020 The cyberspace filtering as a immunization element is a fixed governmental policy of Islamic Republic of IRAN, but it is a challenging problem between policymakers and stockholders, especially after appearance of social networks.
Mohammadsadegh nasrollahi
doaj +1 more source
Aging and Cancer, EarlyView.Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source
RL-RTree: A Reinforcement Learning-Optimized Dynamic R-Tree for High-Dimensional Spatial Indexing
IEEE AccessSpatial indexing in high-dimensional dynamic environments faces critical challenges, including the curse of dimensionality and rapid distribution shifts, which degrade the performance of traditional indexes like R*-trees and static learned indexes.
Yongxin Peng
doaj +1 more source