Results 51 to 60 of about 175,352 (225)

APOE‐stratified Proteomic and Metabolomic Analysis Reveals Mitochondrial Dysfunction Inflammation and Lipid Dysregulation in Alzheimer's Disease

Advanced Science, EarlyView.
A large‐scale multiomic dataset (proteomic and metabolomic) comprising 3,060 plasma samples were analyzed to identify proteins, metabolites, pathways, and protein‐associated drugs linked to Alzheimer’s Disease (AD) independently of apolipoprotein E (APOE). AD was associated with a distinct molecular signature that captures.
Fuhai Li, Yike Chen, Daniel Western, Muhammad Ali, Menghan Liu, Katherine Gong, Ying Xu, Joseph Lowery, David M. Holtzman, Chloe Robins, John D. Eicher, Yen‐Ning Huang, ShiWei Liu, Tamina Park, Andrew J. Saykin, Kwangsik Nho, Mahdi Moqri, Richard C. Mohs, Amelia Farinas, Patricia Moran‐Losada, Hamilton Se‐Hwee Oh, Tony Wyss‐Coray, Carlos Cruchaga   +22 more
wiley   +1 more source

El viaje de Eduard Seler y Caecilie Seler-Sachs por Chiapas y Guatemala, 1896

Indiana
En el transcurso de su segundo viaje (1895-1897), Eduard Seler y Caecilie Seler-Sachs visitaron el estado mexicano de Chiapas y la República de Guatemala, con el fin de estudiar sitios arqueológicos y juntar colecciones de objetos para el Königliches ...
Ulrich Wölfel
doaj   +1 more source

3D Bioprinted Fat‐Myocardium Model Unravels the Role of Adipocyte Hypertrophy in Atrial Dysfunction

Advanced Science, EarlyView.
A human‐derived 3D bioprinted fat–myocardium model is developed to investigate how adipocyte hypertrophy drives atrial dysfunction in obesity. Palmitate‐induced adipocyte hypertrophy promotes adipose dysfunction that impairs atrial cardiomyocyte metabolism and electrophysiology through both paracrine and direct interactions. This platform recapitulates
Lara Ece Celebi, Pinar Zorlutuna
wiley   +1 more source

Passivation‐Induced Species Dynamics and Microstructural Evolution in Solid‐State Lithium–Sulfur Cathodes

Advanced Science, EarlyView.
The formation of insulating Li2S during discharge in solid‐state lithium–sulfur batteries passivate reaction sites and limits sulfur utilization. In this work, a microstructure‐resolved modeling framework coupling transport and reaction kinetics is developed to predict charge–discharge behavior and reveal particle‐scale species evolution and incomplete
Arpan K. Sharma, Bairav S. Vishnugopi, Elif Pınar Alsaç, Matthew T. McDowell, Partha P. Mukherjee   +4 more
wiley   +1 more source

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

Advanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu, Haolin Fan, Minwoo Kim, Tong Zhou, Pinyi Yang, Lingdi Zhao, Yiran Wang, Ziyuan Che, Chia‐Wei Liu, Bingbing Li, Yangzhi Zhu   +10 more
wiley   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Ion‐Pair‐Tuned Ionogels for Broad‐Range Linear Pressure Sensing

Advanced Science, EarlyView.
Ionogels engineered through ion‐pair tuning extend the linear sensing range of capacitive pressure sensors. By balancing ionic mobility and polarizability within the polymer matrix, this approach mitigates dielectric saturation and maintains a stable pressure response across a broad operating range.
Hyeonseo Joo, Tianhao Yu, Yumin Dai, Seokkyoon Hong, Axel González Cornejo, Tristan Michael Long, Sang Mok Park, Pete S. Kollbaum, Edgar Bolívar‐Nieto, Young L. Kim, Dong Rip Kim, Chi Hwan Lee   +11 more
wiley   +1 more source

Impact of Moisture Exposure on Thermal Stability and Safety of Solid‐State Batteries

Advanced Energy Materials, EarlyView.
Sulfide‐based solid‐state batteries (SSBs) hold significant potential for next‐generation energy storage, yet their practical deployment is hindered by the moisture sensitivity of sulfide solid electrolytes. This study examines how moisture exposure influences thermo‐electrochemical instability at the material and cell‐level, and underscores the ...
Md Toukir Hasan, Alvaro J. Miguel, Bairav S. Vishnugopi, Abhinanda Sengupta, Avijit Karmakar, Gordon H. Waller, Corey T. Love, Partha P. Mukherjee   +7 more
wiley   +1 more source

Kenyan Farmers' Policy Priorities During Economic Crisis and Stability: Insights From a Best‐Worst Scaling Experiment

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Amid rising food and fertilizer prices, understanding farmers' policy preferences is critical for effective crisis response. We use best‐worst scaling experiment to assess Kenyan mobile‐owning crop farmers' preferences for government support under high and normal price scenarios.
Mywish K. Maredia, John Olwande, Jacob Ricker‐Gilbert, David L. Mather, Nicole M. Mason   +4 more
wiley   +1 more source

U.S. Consumer Preferences for Cage‐Free Eggs and Hen Housing Policies

Agribusiness, EarlyView.
ABSTRACT Farm animal welfare (FAW) continues to be a divisive issue in the egg industry. In the United States, 10 states and most major retailers have implemented policies or voluntary pledges to transition to 100% cage‐free egg sales. We use best‐worst scaling and discrete choice experiments to evaluate U.S.
Vincenzina Caputo, Aaron J. Staples, Jayson L. Lusk, Glynn T. Tonsor   +3 more
wiley   +1 more source