Results 91 to 100 of about 3,250,923 (288)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Determining the indications and contraindications for psychoanalytic treatment seems crucial to achieve therapeutic success and improve treatment effectiveness.
Marina Bento Gastaud +12 more
doaj
Gravity device for accurate and rapid indication of relative gravity conditions aboard accelerating ...
Boehm, J.
core +1 more source
Periodicity in the Light Curve of P Cygni - Indication for a Binary Companion?
We use observations of the Luminous Blue Variable (LBV) P Cygni spanning seven decades, along with signal processing methods, to identify a periodicity in the stellar luminosity.
Kashi, Amit +2 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The application prospects and development trends of orally disintegrating tablets to dogs
: Orally disintegrating tablets (ODTs) disintegrate rapidly in the mouth in seconds when placed at the tongue. The introduction of ODTs for dogs can address many needs, ranging from convenient dosing for dogs with dysphagia to extending life cycle of ...
Tingting Yi
doaj +1 more source
Analyzing hysterectomies performed at our clinic between 2009 and 2011
Objective: To analyze patients who underwent hysterectomy for benign lesions.Methods: We retrospectively analyzed 711 patients who underwent hysterectomy for benign lesions. Results: Hysterectomy was performed abdominally in 87.2% (n=620) of the patients,
Züleyha Gedik Cevahir +4 more
doaj +1 more source
Philosophy and time travel / Filosofija ir kelionės laiku
The author investigates the topic of philosophy of time travel by explicating how awareness of time helps to understand such time travel, the ways we encounter others, speak with them about the world and events in our world and history.
Algis Mickūnas
doaj +1 more source
Remotely operated gripper provides vertical control rod movement [PDF]
Remote actuation of a gripper shaft affects vertical engagement between a drive shaft and control rod. A secondary function of the gripper is to provide remote indication of positive completion of the gripping or ungripping ...
Hutter, E., Koch, L. J.
core +1 more source

