Results 101 to 110 of about 3,250,923 (288)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Fujita Medical Journal, 2016 Since the first introduction of laparoscopic cholecystectomy, the field of laparoscopic surgery has expanded rapidly to include surgery for other organs, and more complex and technically demanding abdominal surgery.
Zenichi Morise
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
An Annotation Model on End-to-End Chest Radiology Reports
IEEE Access, 2019 Annotating radiographic images with tags is an indispensable preliminary work in computer-aided medical research, which requires professional physician participated in and is quite time-consuming.
Xin Huang +4 more
doaj +1 more source
On a weak Gauss law in general relativity and torsion
, 2012 We present an explicit example showing that the weak Gauss law of general relativity (with cosmological constant) fails in Einstein-Cartan's theory. We take this as an indication that torsion might replace dark matter.Comment: 10 pages.
Blagojević M +7 more
core +3 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Pesquisa Agropecuária Brasileira, 2007 Foram usados dados de produtividade de grãos, de 101 ensaios de competição de cultivares de milho (Zea mays L.), realizados no Estado do Rio Grande do Sul, nos anos agrícolas 2002/2003, 2003/2004 e 2004/2005, com o objetivo de avaliar estatísticas para a
Alberto Cargnelutti Filho +1 more
doaj +1 more source
Search for periodicities near 59 s in the COS-B gamma-ray data of 2CG195+04 (Geminga) [PDF]
, 1985 The COS-B data relating to five observations in the general direction of Geminga, spanning 6.7 years, were searched for pulsation near 59 s. The SAS-2 indication is not confirmed. An indication of a 59 s pulsation in the gamma ray emission from 2CG195+04
Bennett, K. +7 more
core +1 more source
Indication of the ferromagnetic instability in a dilute two-dimensional electron system
, 2001 The magnetic field B_c, in which the electrons become fully spin-polarized, is found to be proportional to the deviation of the electron density from the zero-field metal-insulator transition in a two-dimensional electron system in silicon.
A. A. Shashkin +22 more
core +2 more sources