Results 141 to 150 of about 4,059,966 (338)

Hanefî Fıkhında ve Usûlünde Sözün Mûcebi-Muhtemeli Ayırımı

Rize İlahiyat Dergisi
Gerek fıkıh usûlü gerekse fürû-ı fıkıh kaynaklarının ilgili bahislerinde, lafızlardan ve sözlerden anlaşılan manaların İslam hukukçularınca en genel şekliyle “sözün mûcebi” ve “sözün muhtemeli” olmak üzere iki sınıf olarak kategorize edildiği ...
Üveys Ateş
doaj   +1 more source

Assessing the use of Geographical Indications for the New England wine region in NSW [PDF]

Geographical Indications (GIs) have increasingly been used as a marketing tool to create an image of quality and uniqueness, and so capture premium prices.
Campbell, Gene, Chang, Hui-Shung (Christie), Sniekers, Peter   +2 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

The Impact of Tracheostomy Indication on Patient Outcomes and Hospital Course

Laryngoscope Investigative Otolaryngology
Objective The purpose of this study is to better understand the prognostic implications for a patient's hospital course, chances for ventilator liberation and decannulation, functional status, and mortality based on the indication for tracheostomy ...
Ryan C. Higgins, Kaeli Samson, Duncan Works, Jayme R. Dowdall   +3 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Trends in Cesarean Section in a Tertiary Referral Hospital: Time-Series Analysis

Central Asian Journal of Medical Sciences
Objectives: To analyze the causes and indications of C-sections conducted at the tertiary referral center and to forecast future patterns. Methods: We retrospectively analyzed 25,311 delivery records from 2013 to 2022 at the National Center for Maternal ...
Davaasambuu Enkhmaa, Oyunkhand Enkhtaivan, Baljinnyam Batsuuri, Nasantogtokh Erdenebileg, Tsedmaa Baatar, Shinetugs Bayanbileg, Tsolmon Khadaa, Khishgee Seded, Khalid Sharifi, Altantuya Shirchinjav   +9 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source