Strategies for robust, accurate, and generalizable benchmarking of drug discovery platforms. [PDF]
BioinformaticsVan Norden M +3 more
europepmc +1 more source
Cut‐off value of nuchal translucency as indication for chromosomal microarray analysis
Ultrasound in Obstetrics and Gynecology, 2017 I. Maya +12 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Less endocrine therapy in HR+/HER2- breast cancer: a nationwide trend despite unchanged guidelines. [PDF]
BreastVerreck EEF +8 more
europepmc +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Incidence of Adrenal Masses Eventually Discovered in Patients Screened for Primary Aldosteronism.
J Clin Endocrinol MetabKline GA +7 more
europepmc +1 more source
Risk of New Indications for Anticoagulants and Thrombolytics in People With Cognitive Impairment: Implications for Anti-Amyloid Therapy. [PDF]
NeurologyParks AL +9 more
europepmc +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Letter to the editor regarding: "influence of proton pump inhibitor use on clinical outcomes of patients with inflammatory bowel disease". [PDF]
Ann MedGong Q, Jin R.
europepmc +1 more source