Results 181 to 190 of about 1,594,269 (319)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

DualKG-DC: A Drug-Centric Dual-Layer Knowledge Graph Framework for Drug Combination Prediction. [PDF]

J Med Syst
Gao Z, Perkins SW, Parameswaran S, Xu R.
europepmc   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Durability of One- and Two-Level Lumbar Fusion Surgeries: A Survivorship Analysis Based on Revision Surgery Rates. [PDF]

J Am Acad Orthop Surg Glob Res Rev
Dillibabu S, Crawford CH, Carreon LY, Mathew J, Gum JL, Djurasovic M, Glassman SD.   +6 more
europepmc   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Reverse Total Shoulder Arthroplasty: Biomechanics and Indications

Current Reviews in Musculoskeletal Medicine, 2019
Caitlin M. Rugg, M. Coughlan, Drew A. Lansdown   +2 more
semanticscholar   +1 more source

Estimation of Future Patient Populations Eligible for Radioligand Therapies in the EU and the UK: A Modelling Study. [PDF]

Lancet Reg Health Eur
Holzwarth U, Cirillo R, Goulart M, Hernandez D, Peristeris P, Poschenrieder A, Papaioannou P, Kanavos P, la Fougère C, Schaetz L.   +9 more
europepmc   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Indications of over- and undertreatment of hypothyroidism in primary care: a scoping review and evidence mapping. [PDF]

Scand J Prim Health Care
Sloth BN, Blumenfeld MB, Kristensen JK, Brink Valentin J, Carlé A, Thomsen JL.   +5 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source