Results 201 to 210 of about 1,087,779 (244)

New Perspectives on Analyzing and Interpreting Base Running Efficiency: A GPS Approach. [PDF]

Sensors (Basel)
Martínez-Rodríguez JA, Neville J, Cronin JB.   +2 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

A transcriptional atlas of gyrification reveals dynamic spatio-temporal gene expression in the developing ferret cortex. [PDF]

Brain Struct Funct
Barresi M, Johnstone A, Quezada S, Quigley A, Tolcos M.   +4 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Multi-pathogen serosurveillance in Tonga examining demographic correlates and geographic clustering of 17 pathogens. [PDF]

Sci Rep
Lawford HLS, Tukia O, Takai J, Sheridan S, Ward S, Jian H, Martin BM, 'Ofanoa R, Vaccher S, Angrisano F, Robinson LJ, Lau CL.   +11 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Wolf in Sheep's Clothing: A Case of Sarcoidosis Exacerbating Asthma. [PDF]

Cureus
Pan M, McCracken J.
europepmc   +1 more source

ICU-Acquired Weakness: Diagnostic Yield of a Clinical Diagnosis with Additional Quantification of Myosin Loss in Adult Critically Ill Patients. [PDF]

J Clin Med
Adema W, Exl MT, Hedström Y, Larsson L, Schefold JC, Z'Graggen WJ.   +5 more
europepmc   +1 more source