Results 71 to 80 of about 8,970,332 (246)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Afp and Hcg in Germ Cell Tumors
The International Journal of Biological Markers, 1994 The high specificity and sensitivity of testicular tumor markers make them particularly useful in the management of these neoplasms. Basal value represents an independent prognostic variable, influencing the choice of therapy. An increase in marker level
M.A. Bassetto +7 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
The clinical investigation of static and dynamic balance
B-ENT, 2008 The clinical investigation of static and dynamic balance. This article describes the clinical examination of static and dynamic balance. The purpose is to illustrate the guideline for the diagnosis and management of vertigo.
S. Dejardin
doaj +2 more sources
A Case of a Ruptured Sclerosing Liver Hemangioma
International Journal of Hepatology, 2011 Hemangiomas are the most common benign tumors found in the liver, typically asymptomatic, solitary, and incidentally discovered. Although vascular in nature, they rarely bleed. We report a case of a 52-year-old woman with a previously stable hemangioma
Haris Papafragkakis +5 more
doaj +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
The standard for risk management in portfolios, programs, and projects
, 2019 The Standard for Risk Management in Portfolios, Programs, and Projects is an update and expansion upon PMI's popular reference, The Practice Standard for Project Risk ...
Project Management Institute
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Russian Journal of Economics and Law, 2019 Objective: to develop methods for constructing small predictive systems for determining the changing trends of the economic situation.Method: process, system, abstract-logical, conceptual-methodological methods.Results: the scientific approaches to the ...
G. A. Shcherbakov
doaj +1 more source
The standard for program management
, 2017 The Standard for Program Management – Fourth Edition differs from prior editions by focusing on the principles of good program management. Program activities have been realigned to program lifecycle phases rather than topics, and the first section was ...
Project Management Institute +1 more
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