Results 201 to 210 of about 4,248,566 (303)

Establishment and application of safety evacuation scheme evaluation model with entropy weight and TOPSIS for university dormitories in China. [PDF]

Sci Rep
Huang Y, Lu S, He Z, Ma S, Yu H, Pan X, Huang W.   +6 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Measuring the quality of species list governance. [PDF]

Bioscience
Garnett ST, Bánki O, Barik SK, Berryman AJ, Bouchard P, Buckeridge J, Christidis L, Cigliano MM, Conix S, Crawford-Weaver H, van Dijk PP, Evenhuis NL, Hilton-Taylor C, Hobern D, Johnston C, Klopper RR, Kroh A, Le Roux M, Pape T, Pyle RL, Raz L, Thomas P, Thomson S, Vandepitte L, Wambiji N, Zachos FE, Lien AM.   +26 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Optimizing pharmacogenomic clinical decision support: a usability study of epic's Genomic-Indicators. [PDF]

BMC Pharmacol Toxicol
Hong JJ, Hall BT, Azeem S, Jacobs DA, Hogan GC, Norris ML, Cicali EJ, Duarte JD, Cavallari LH, Nguyen KA.   +9 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Physical Activity Indicators Among Children and Adolescents in Lebanon, Qatar, and the United Arab Emirates: Comparative Synthesis of Active Healthy Kids Report Card Data From 1998 to 2022.

JMIR Public Health Surveill
Baghestani A, Majed L, Lock M, Alrahma A, Abi Nader P, Sayegh S, Al-Mohannadi AS, Nauman J, Aubert S, Tremblay MS, Loney T.   +10 more
europepmc   +1 more source

Attainment of English and maths between 16 and 19. Impact indicator. 4, Proportion of young people attaining level 2 in English and maths (of those who did not achieve this by age 16) [PDF]

, 2014

core  

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Understanding the factors influencing antipsychotic medication use in continuing care during the COVID-19 pandemic: a qualitative descriptive study. [PDF]

BMJ Open
Karimi-Dehkordi M, Asaana P, Wagg A, Hanson HM, Harasym P.   +4 more
europepmc   +1 more source