Results 101 to 110 of about 2,931,829 (352)

The discontinuous nature of chromospheric activity evolution

open access: yes, 2010
Chromospheric activity has been thought to decay smoothly with time and, hence, to be a viable age indicator. Measurements in solar type stars in open clusters seem to point to a different conclusion: chromospheric activity undergoes a fast transition ...
A. Skumanich   +39 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

How to compute the Frobenius-Schur indicator of a unipotent character of a finite Coxeter system

open access: yes, 2013
For each finite, irreducible Coxeter system $(W,S)$, Lusztig has associated a set of "unipotent characters" $\Uch(W)$. There is also a notion of a "Fourier transform" on the space of functions $\Uch(W) \to \RR$, due to Lusztig for Weyl groups and to Brou\
Adin   +36 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Development of analytical model for managing emergency preparedness and response system to nuclear power facility accident [PDF]

open access: yesE3S Web of Conferences
In this work, a control model of the emergency preparedness system for nuclear and radiation accidents was synthesized, a block diagram of the control system of the emergency preparedness system for nuclear and radiation accidents was developed, and the ...
Burlov Vyacheslav   +3 more
doaj   +1 more source

GPS-guided mobile robot platform featuring modular design elements for agricultural applications : a thesis presented in partial fulfilment of the requirements for the degree of Masters of Engineering in Mechatronics at Massey University Turitea Campus, Palmerston North, New Zealand [PDF]

open access: yes, 2016
The agricultural industry has not seen significant innovation in development of low-cost automated farming solutions, with current systems costing several thousands of dollars to implement.
Corpe, Samuel John Oldfield
core  

Extreme plurisubharmonic singularities

open access: yes, 2012
A plurisubharmonic singularity is extreme if it cannot be represented as the sum of non-homothetic singularities. A complete characterization of such singularities is given for the case of homogeneous singularities (in particular, those determined by ...
Rashkovskii, Alexander
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Transdisciplinary models of hydraulic drives of mobile machinery

open access: yesСистемный анализ и прикладная информатика, 2019
Modern drive engineering requires a comprehensive analysis of all work processes in hydraulic drives, solving the problems of modeling the technological processes of their production using mathematical and software tools of various physicality.The ...
A. V. Puzanov
doaj   +1 more source

Tools for reformulating logical forms into zero-one mixed integer programs (MIPS) [PDF]

open access: yes, 1992
A systematic procedure for transforming a set of logical statements or logical conditions imposed on a model into an Integer Linear Programming (ILP) formulation or a Mixed Integer Programming (MIP) formulation is presented.
Lucas, CA, Mitra, G, Moody, S
core  

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