Results 111 to 120 of about 2,931,829 (352)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Renormalising Feynman diagrams with multi-indices

45 ...
Bruned, Yvain, Hou, Yingtong
openaire   +2 more sources

Phase separation versus supersolid behavior in frustrated antiferromagnets

, 2011
We investigate the competition between spin-supersolidity and phase separation in a frustrated spin-half model of weakly coupled dimers. We start by considering systems of hard-core bosons on the square lattice, onto which the low-energy physics of the ...
A. F. Andreev, A. Fabricio Albuquerque, Frédéric Mila, Jean-David Picon, M. Takigawa, Nicolas Laflorencie   +5 more
core   +3 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

E-Healthcare Improvement through the Design of a Cloud-Based Blood Supply Chain: A System Dynamics Approach [PDF]

مدیریت مهندسی و رایانش نرم
In this paper, we adopt a system dynamics approach to examine the behavior of the blood supply chain (BSC), focusing on the key performance indicator "deviation from optimal stock coverage" and the key factors "donation utility," "donation queue," and ...
Saeed Abdolhossein Zadeh, Mostafa Zandieh, Akbar Alam-Tabriz   +2 more
doaj   +1 more source

Hubble Diagram of Gamma-Rays Bursts calibrated with Gurzadyan-Xue Cosmology

, 2008
Gamma-ray bursts (GRBs) being the most luminous among known cosmic objects carry an essential potential for cosmological studies if properly used as standard candles.
Cuesta, H. J. Mosquera, Furlanetto, C., Khachatryan, H. G., Mirzoyan, S., Turcati, R., Yegorian, G.   +5 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Assessing diagnostic applicability of heat release characteristics determined based on ship engine indicator diagrams [PDF]

, 2009
S. Polanowski
openalex   +1 more source

Identification of the Lithium Depletion Boundary and Age of the Southern Open Cluster Blanco 1

, 2010
We present results from a spectroscopic study of the very low mass members of the Southern open cluster Blanco 1 using the Gemini-N telescope. We obtained intermediate resolution (R~4400) GMOS spectra for 15 cluster candidate members with I~14-20 mag ...
Baraffe, Barrado y Navascués, Barrado y Navascués, Bildsten, Bochanski, Burke, Cargile, Cargile, Carpenter, Cayrel, Chabrier, Edvardsson, Nidever, Schaller, Skrutskie, Stauffer, Stauffer, Stauffer, Stauffer, Ushomirsky, Yee   +20 more
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source