Investigation of the Thermodynamic Process of the Refrigerator Compressor Based on the m-θ Diagram
The variation of refrigerant mass in the cylinder of refrigerator compressor has a great influence on the compressor’s thermodynamic process. In this paper, the m-θ diagram, which represents the variation of refrigerant mass in compressor cylinder (m ...
Tao Wang +3 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
The Sylvester problem and uniqueness sets in classes of entire functions
In this paper, we study the problem of finding, by a chosen sequence of complex numbers tending to infinity, the widest possible class of entire functions in a given scale for which this sequence is a uniqueness set.
G. G. Braichev
doaj +1 more source
PENERAPAN DIAGRAM VEE DALAM PEMBELAJARAN BERBASIS MASALAH UNTUK MENINGKATKAN KEMAMPUAN BERPIKIR KRITIS DAN METAKOGNISI PADA MATERI SISTEM RESPIRASI [PDF]
Penelitian ini bertujuan untuk menganalisis pengaruh penerapan Diagram Vee dalam Pembelajaran Berbasis Masalah terhadap peningkatan kemampuan berpikir kritis dan metakognisi siswa pada materi sistem respirasi manusia.
Laelasari, Iseu
core
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
FAULT DIAGNOSIS OF PUMPING UNIT BASED ON GLOBAL AND LOCAL FEATURES
In order to accurately and timely judge the fault location of pumping unit and change the inefficient manual fault diagnosis mode, a fault identification method of pumping unit based on Mahalanobis Taguchi system was proposed . Firstly, the geometric and
ZHAO XinYu, FAN Jun, HE Fang, TANG LiWen
doaj
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
METHODOLOGY FOR DETERMINING INDICATORS OF DIESEL 4DTNA1 DURING ROAD TESTING [PDF]
The paper presents a methodology for determining the technical and economic parameters of automobile diesel during the road test. Recent testing techniques during testing of small class bus RUTA-25d, equipped with a domestic car diesel engine 4DTNA1 are ...
Gritsuk, O. +2 more
doaj
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source

