Results 161 to 170 of about 5,013,010 (305)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Informing indicator species selection by combining species associations and environmental responses. [PDF]

Ecol Appl
Rissanen T, Sirén J, Mäkipää R, Vanhatalo J, Laine AL.   +4 more
europepmc   +1 more source

Wildfire and the ecological niche: Diminishing habitat suitability for an indicator species within semi-arid ecosystems. [PDF]

Glob Chang Biol, 2020
O'Neil ST, Coates PS, Brussee BE, Ricca MA, Espinosa SP, Gardner SC, Delehanty DJ.   +6 more
europepmc   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Identification of Farmland Bird Indicator Species for Practitioner Monitoring in the United Kingdom. [PDF]

Ecol Evol
McHugh NM, Ness ER, Nichols R, Banks G, Strong D, Young MW, Zuta A, Begg GS.   +7 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Delisting a species: Section 4 of the Endangered Species Act

, 2013
The goal of the Endangered Species Act (ESA) is to conserve endangered and threatened species. Species are added to the Federal List of Endangered and Threatened Wildlife and Plants in order to regulate activities that may impact them.

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Effects of Management and Climatic Variability on Indicator Species and Biomass Production in Carpathian Mountain Grasslands. [PDF]

Plants (Basel)
Ghețe I, Mihaela B, Șerban C, Ghețe A.   +3 more
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Biodiversity Conservation through Public Management in Cultural Landscapes: Integrating Economic and Ecological Evaluation of Species by Shadow Prices [PDF]

The paper deals with the problem of finding relative values for species in the case of biodiversity conservation in a cultural landscape. We use the concept of shadow prices to derive flexible functional forms that allow us to conduct an interactive and ...
Nuppenau, Ernst-August
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