Results 201 to 210 of about 4,980,966 (341)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Quality indicators for deceased organ and tissue donation for transplantation: a scoping review protocol. [PDF]

Syst Rev
da Silva Pimentel RR, Tronchin DMR, Dos Santos MJ, Martins MS, Brito ÁN, Santana FLP.   +5 more
europepmc   +1 more source

The Establishment Performance Measures and Indicators for Social Housing in Ontario – The Background and the Process: What Are the Challenges?

, 2004
Kathyrn Zarfas
openalex   +1 more source

DISTENDER indicators for Round2a (climate and socioeconomic signal) and for: Air Quality and Emissions; Urban Heat Island; Health; Water; Energy; Agroforestry; Sectorial economy; Risk and Vulnerability. Case study: Austria. Global climate model: Ind. Scenario: SSP245.

DISTENDER, ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON UOA, UNIVERSIDADE DE AVEIRO, UNIVERSITAT ZU KOLN, CLIMATE SOLUTIONS UNIPESSOAL LDA, UNIVERSIDAD POLITECNICA DE MADRID, UK CENTRE FOR ECOLOGY & HYDROLOGY   +6 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Constructing an indicator system for factors influencing volleyball coaches' in-game tactical decision-making: a Delphi study. [PDF]

Front Psychol
Sun Z, Zhang F.
europepmc   +1 more source

The difference of indicators among the three groups before and after 12-week physical education.

Qing Chang (93814), Xingrui Han (22662459), Wenlong Shen (9313937), Baoyi Yang (22662462), Zongrui Lin (22662465)   +4 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Construction of an index system for assessing emergency department overcrowding in Chinese tertiary hospitals: a Delphi study. [PDF]

BMC Emerg Med
Ren Z, Xu N, Yang Y, Li S, Zhang H, Wang L, Mu YN, Chong W, Zhou P, Pan L, Wang G, Li X, Li Y, Liu W, Liu H, Xu B, Jin Y, Ma L, Feng G, Ma Q.   +19 more
europepmc   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source