External quality assessment for nucleic acid quantitative testing of human hepatitis B and hepatitis C virus in Chongqing, China: 2009-2024. [PDF]
Guo Y+6 more
europepmc +1 more source
Health Basket and Health Block Grants Guidelines for the Disbursement of Funds, Preparation of Comprehensive Council Health Plans, Financial and Technical Reports and Rehabilitation of PHC Facilities by Councils [PDF]
Ministry of Health and Social Welfare, (MoHSW)+1 more
core
Human health benefit and burden of the schizophrenia health care pathway in Belgium : paliperidone palmitate long-acting injections [PDF]
De Smedt, Delphine+4 more
core +1 more source
ABSTRACT Objective The Apolipoprotein (APOE) ε4 allele is the strongest genetic risk factor for late‐onset Alzheimer's disease (AD); however, many ε4 carriers remain cognitively intact into old age. Leveraging plasma neuron‐derived extracellular vesicles (NDEVs), we sought to identify biomarkers of cognitive resilience and their interplay with APOE ...
Apostolos Manolopoulos+17 more
wiley +1 more source
Implementation of the laboratory strategic framework to strengthen health laboratory services in Eastern Mediterranean Region, 2016-2023. [PDF]
Mosha FS+4 more
europepmc +1 more source
Repeat Expansions in PLIN4 Cause Autosomal Dominant Vacuolar Myopathy With Sarcolemmal Features
ABSTRACT Objective We aim to describe and characterize two unrelated Spanish families suffering from an autosomal dominant autophagic vacuolar myopathy caused by repeat expansions in PLIN4. Methods We evaluated the clinical phenotype and muscle imaging, and performed a genetic workup that included exome sequencing, muscle RNAseq, and long‐read genome ...
Laura Llansó+17 more
wiley +1 more source
Experimental Study on the Effect of Ultraviolet Light on Spontaneous Combustion of Coal under the Action of a Photosensitive Reagent. [PDF]
Zhang X+6 more
europepmc +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio+11 more
wiley +1 more source
Constructing a Resilience Assessment Index System for Tuberculosis Healthcare Services Under Public Health Emergencies: A Modified Delphi Study. [PDF]
Fan M+7 more
europepmc +1 more source