Results 71 to 80 of about 2,298,868 (224)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

The role of GIS and remote sensing in tracking vegetation cover in the Tlagh and El-Abed Basins (Northeastern Morocco) from 1986 to 2018 [PDF]

open access: yesE3S Web of Conferences
The Tlagh and El-Abed basins in the Taourirt-Guercif corridor are known for their diverse plant cover, especially in species naturally present for generations, termed 'inherited species'.
Mouadili Omar, Sbai Abdelkader
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Exponential Inflation with $F(R)$ Gravity

open access: yes, 2018
In this paper we shall consider an exponential inflationary model in the context of vacuum $F(R)$ gravity. By using well-known reconstruction techniques, we shall investigate which $F(R)$ gravity can realize the exponential inflation scenario at leading ...
Oikonomou, V. K.
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Estimation of the Lithuanian tax system according to j. Gill‘s diagnostic indices

open access: yesBusiness, Management and Education, 2010
Theorists and practicians have various solutions on offer for estimating and improving the tax system. However, the tax system is a complicated combination, which calls for a systematic attitude and combined evaluation.
Ilona Skačkauskienė
doaj   +1 more source

Background Indicators [PDF]

open access: yesEconometrics, 2019
It is customary to assume that an indicator of a latent variable is driven by the latent variable and some random noise. In contrast, a background indicator is also systematically influenced by variables outside the structural model of interest. Background indicators deserve attention because in empirical work they are difficult to distinguish from ...
openaire   +4 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

RATING ANALYSIS OF THE LEVEL OF DIGITAL TRANSFORMATION OF THE ECONOMIES OF EAEU AND EU THE COUNTRIES

open access: yesЦифровая трансформация, 2018
The article considers the problem of assessing the level of development in the country of the digital economy with the help of international ICT ratings, their shortcomings are analyzed.
G. G. Goloventchik
doaj  

An evaluation of population indices for northern bobwhite

open access: yesWildlife Society Bulletin, 2019
Northern bobwhite (Colinus virginianus) populations are monitored using 2 general approaches—population indices and abundance estimators. Due to their convenient sampling designs, indices are commonly used by land managers and researchers to predict or ...
Bradley W. Kubečka   +5 more
doaj   +1 more source

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