Results 41 to 50 of about 149,906 (300)

An Injectable Electroactive Hydrogel Engineered for Stable Bioelectronic Interfaces

Advanced Materials Interfaces, EarlyView.
Injectable electroconductive hydrogels enable soft, conformal, and stable bioelectronic interfaces for electroceutical therapies. A catechol‐modified hyaluronic acid/alginate/edge‐functionalized graphene platform combines wet adhesion, shear‐thinning injectability, tissue‐matched mechanics, and electrochemical functionality.
Ying Zhou, Peng Zheng, Beverley Cheung, Chien Yu Huang, Greg Ryder, Jonathan R Clark, D S Abdullah Al Maruf, Yi‐Hui Wu, Ming‐Dou Ker, Xufeng Huang, Gordon G Wallace, Xiao Liu   +11 more
wiley   +1 more source

The development of guidelines for indigenous research ethics in Aotearoa/New Zealand. [PDF]

, 2016
The development of Indigenous frameworks for research ethics has been a key component of progressing Indigenous aspirations for research around the world.
Hudson, Maui, Milne, Moe, Smith, Barry, Russell, Khyla, Atatoa-Carr, Polly, Reynolds, Paul   +5 more
core  

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source

Ensuring Indigenous co-leadership in health research: a Can-SOLVE CKD case example

International Journal for Equity in Health, 2023
Background Indigenous people are insightful and informed about their own health and wellness, yet their visions, strengths and knowledge are rarely incorporated into health research.
Cathy Woods, Craig Settee, Mary Beaucage, Helen Robinson-Settee, Arlene Desjarlais, Evan Adams, Catherine Turner, Malcolm King, Letitia Pokiak, Mary Wilson, Evelyn Voyageur, Chantel Large, Jonathan McGavock, Joanne Kappel, Helen Chiu, Tamara Beardy, Isabelle Flett, James Scholey, Heather Harris, Jocelyn Jones, Latash Maurice Nahanee, Delhia Nahanee, on behalf of the Can-SOLVE CKD Indigenous Peoples’ Engagement, Research Council (IPERC)   +22 more
doaj   +1 more source

Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean

Advanced Science, EarlyView.
This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma, Hanyu Zhao, Haojie Feng, Xulun Dong, Lin Chen, Mingliang Yang, Runyi Chen, Chengjun Lei, Chunyan Liu, Qingshan Chen, Dawei Xin, Jinhui Wang   +11 more
wiley   +1 more source

Extracellular Vesicle‐Transferred ATP‐Citrate Lyase Induces Monocyte Differentiation Toward Tumor‐Associated Macrophages and Fuels Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
Hepatocellular carcinoma (HCC)‐derived extracellular vesicles (EVs) enrich the metabolic enzyme ATP‐citrate lyase (ACLY). EV‐transferred ACLY enhances palmitate biosynthesis, increases the S‐palmitoylation and stability of multiple immune checkpoint proteins, augments the cellular immunosuppressive activity, and ultimately accelerates the malignant ...
Zhijun Liu, Haihong Lai, Qing Yang, Chaoyue Zhang, Bin Jia, Qiyi Chen, Yuling Deng, Fen Cao, Yuyu You, Zhe Li, Dongming Kuang, Bo Li   +11 more
wiley   +1 more source

Our lands tell our stories: supporting Indigenous co-led research through the Indigenous Foods Knowledges Network

Arctic Science
The Indigenous Foods Knowledges Network (IFKN) brings together Indigenous researchers and community leaders from the Arctic and U.S. Southwest along with non-Indigenous researchers to foster cross-cultural interdisciplinary knowledge exchange about ...
Mary Beth Jäger, Noor Johnson, Eva Burk, Nels Christensen, Daniel B. Ferguson, Samantha Honani, Orville Huntington, Shawna Larson, Lydia Jennings, Michael Kotutwa Johnson, Amy Juan, Colleen Strawhacker, Max Taylor, Wendy F. Todd, Althea Walker, Stephanie Russo Carroll   +15 more
doaj   +1 more source

Large‐Scale Genomics Reveals Three‐Source Ancestry and Layered Adaptation to High Altitude in Tibetan Chickens

Advanced Science, EarlyView.
Whole‐genome analysis of 1,054 chickens reveals three ancestral sources (NWC, SYA, and SHF) with distinct temporal entry patterns into the Tibetan Plateau. Route‐specific selection scans, calibrated against a demographic null, suggest complementary functional enrichments—vascular homeostasis (NWC), calcium signaling and cardiac adaptation (SYA), and ...
Zongyi Zhao, Ruixue Nie, Hailu Fan, Tenzin Ngodroup, Li Zhu, Hongbin Pan, Bo Zhang, Hao Zhang   +7 more
wiley   +1 more source

Tuberculosis screening indicators in indigenous population in Colombia: a mixed methods research

Cadernos de Saúde Pública, 2022
This study aims to evaluate, via a mixed methods study, the implementation of the screening process for pulmonary tuberculosis (PTB) within indigenous population of the Department of Cauca, Colombia, during the 2016-2018 period. Indicators assessing the PTB screening process were elaborated and estimated.
Iader Rodríguez-Márquez, Kelly Yoana Tello-Hoyos, Pilar Torres-Pereda, Bertha Leonor Guzmán-Salazar, Freddy Pérez, Jhon Edwin Polanco-Pasaje   +5 more
openaire   +4 more sources

Multi‐Omics Insights Into the Mechanisms of Early Muscle Fiber Difference and Transformation Between Lean‐Type and Chinese Indigenous Pigs

Advanced Science, EarlyView.
Multi‐omics analyses uncover breed‐specific cis‐regulatory landscapes and higher‐order chromatin architectural differences that underlie early postnatal muscle fiber divergence in pigs. A super‐enhancer upstream of PPP3CB recruits MEF2C to activate PPP3CB transcription, while the PPP3CB–MEF2C positive feedback loop promotes oxidative muscle fiber ...
Shuailong Zheng, Hainan Wu, Min Liu, Kunpeng Wu, Shuntao Huang, Zulfiqar Ahmed, Lenox Pius, Mengjin Zhu, Dequan Xu   +8 more
wiley   +1 more source