Results 91 to 100 of about 10,481,084 (312)

Character Association and Path Coefficient Analysis for Yield and its Component Traits in Ridge Gourd [Luffa acutangula (L.) Roxb.] Genotypes

open access: yesInternational Journal of Economic Plants
The present investigation was carried out during kharif (July–October, 2025) at the Agricultural Research Station, Kalloli, University of Agricultural Sciences, Dharwad with an aim to assess character association and to determine the direct and indirect
B. Harsha   +4 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

The Role of Organizational Factors in Enabling, and of Autonomy in Potentializing Intrapreneurial Behavior: Mechanisms and Preconditions

open access: yesBAR: Brazilian Administration Review
Objective: the study explores the complex interaction between intrapreneurial behavior, organizational factors, and individual characteristics, with a focus on a moderated-mediation model. This model incorporates individual autonomy as a key enhancer and
Alex de Souza Santana   +3 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Habitat coupling mediates trophic cascades in an aquatic community

open access: yesEcosphere, 2019
Trophic cascades and other indirect effects can significantly mediate community interactions. Movement of energy between systems has been shown to be important for trophic cascades in food webs, where coupling between habitats can be important for food ...
Maria H. K. Marklund   +2 more
doaj   +1 more source

Pneumococcal Meningitis in Adults after Introduction of PCV7 and PCV13, Israel, July 2009–June 2015

open access: yesEmerging Infectious Diseases, 2018
The indirect effect of pneumococcal conjugate vaccine on adult pneumococcal meningitis has not been thoroughly investigated. We present data from active surveillance on pneumococcal meningitis in adults in Israel occurring during July 2009–June 2015 ...
Gili Regev-Yochay   +10 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Aligning mountain lion hunting seasons to mitigate orphaning dependent kittens

open access: yesWildlife Society Bulletin, 2018
Hunting results in direct numerical effects and numerous indirect effects on game species. One indirect effect occurs when a female is killed; and as a consequence, her dependent offspring die, negatively affecting recruitment rates.
Connor O'malley   +4 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Food Additives and Human Health - Indirect Additives

open access: yes, 2020
Indirect food additives are the additives that are not intended to be added directly to foods but are added to food contact articles namely, food packaging.
Ribeiro-Santos, Regiane   +7 more
core   +1 more source

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